Concepedia

Potency Prediction

Potency Prediction is a computational or statistical methodology used in pharmacological research to quantify the expected biological activity of a compound, distinguishing it by its specific focus on estimating the concentration-response relationship that determines the strength of a drug's effect relative to a target.

317

Publications

22.8K

Citations

1.6K

Authors

556

Institutions

Publications per year

2017–2026

98

Parents

Publications

317

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

, , +12

Interpretation of machine learning models using shapley values: application to compound potency and multi-target activity predictions

Raquel Rodríguez-Pérez, Jürgen Bajorath · Journal of Computer-Aided Molecular Design · 2020 · 694 citations · Full text

, , +17

Synthetic Competitive Antagonists of Corticotropin-Releasing Factor: Effect on ACTH Secretion in the Rat

Jean Rivier, Catherine Rivier, Wylie Vale · Science · 1984 · 475 citations

, , +14

Predicted-no-effect concentrations for the steroid estrogens estrone, 17β-estradiol, estriol, and 17α-ethinylestradiol

Daniel J. Caldwell, Frank Mastrocco, Paul Anderson et al. · Environmental Toxicology and Chemistry · 2012 · 365 citations

, , +16

Advancing Drug Discovery through Enhanced Free Energy Calculations

Robert Abel, Lingle Wang, Edward Harder et al. · Accounts of Chemical Research · 2017 · 359 citations

, , +16

1–5 of 317

Authors

1.6K

  1. JB
    Jürgen Bajorath

    University of Bonn, Germany

    11 publications · 971 citations

    11

    h-index

  2. DA
    David A. Basketter

    Unilever (United Kingdom), United Kingdom

    9 publications · 618 citations

    9

    h-index

  3. RA
    Robert Abel

    Schrodinger (United States), United States

    8 publications · 861 citations

    8

    h-index

  4. IK
    Ian Kimber

    AstraZeneca (United Kingdom), United Kingdom

    7 publications · 680 citations

    7

    h-index

  5. SB
    Sathesh Bhat

    Schrodinger (United States), United States

    4 publications · 229 citations

    4

    h-index

1–5 of 1.6K

Institutions

556

  1. University of Bonn

    Bonn, Germany

    11 h-index

    26 publications

    2.1K citations

  2. Schrodinger (United States)

    New York, United States

    9 h-index

    44 publications

    4.5K citations

  3. Unilever (United Kingdom)

    London, United Kingdom

    9 h-index

    26 publications

    2K citations

  4. National Institutes of Health

    Bethesda, United States

    6 h-index

    23 publications

    1.3K citations

  5. Nanjing University

    Nanjing, China

    5 h-index

    10 publications

    281 citations

  6. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    5 h-index

    12 publications

    987 citations

  7. Environmental Protection Agency

    Washington, United States

    4 h-index

    16 publications

    798 citations

  8. Scripps Research Institute

    San Diego, United States

    4 h-index

    25 publications

    1.5K citations

1–8 of 556

Venues

  1. Journal of Medicinal Chemistry

    18 publications · 1.2K citations

    17

    h-index

  2. Journal of Chemical Information and Modeling

    JCIM · 15 publications · 735 citations

    14

    h-index

  3. PubMed

    Repository · 8 publications · 192 citations

    8

    h-index

  4. Biometrics

    7 publications · 418 citations

    7

    h-index

  5. Scientific Reports

    6 publications · 168 citations

    6

    h-index

1–5