Concepedia

Positive Allostery

Positive Allostery is an allosteric regulatory mechanism in which the binding of a ligand at an allosteric site enhances the protein's functional activity at its primary active site.

13

Publications

529

Citations

76

Authors

22

Institutions

Publications per year

2017–2026

3

Parents

Publications

13

Structural insights into probe-dependent positive allosterism of the GLP-1 receptor

Ana B. Bueno, Bingfa Sun, Francis S. Willard et al. · Nature Chemical Biology · 2020 · 95 citations

, , +16

Allostery governs Cdk2 activation and differential recognition of CDK inhibitors

Abir Majumdar, David J. Burban, Joseph M. Muretta et al. · Nature Chemical Biology · 2021 · 72 citations · Full text

, , +13

Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids

Sun-Joo Lee, Feifei Ren, Eva‐Maria Zangerl‐Plessl et al. · The Journal of General Physiology · 2016 · 71 citations · Full text

, , +17

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases

John D. Laughlin, J.C. Nwachukwu, Mariana Figuera-Losada et al. · Structure · 2012 · 49 citations · Full text

, , +12

The First Example of Positive Allosterism in an Aqueous Saccharide-Binding System Designed on a Ce(IV) Bis(porphyrinate) Double Decker Scaffold

Atsushi Sugasaki, Masato Ikeda, Masayuki Takeuchi et al. · Tetrahedron · 2000 · 43 citations

, , +8

1–5 of 13

Authors

76

  1. SS
    Seiji Shinkai

    Kyushu University, Japan

    1 publications · 43 citations

    1

    h-index

  2. RB
    Ricky B. Nellas

    University of the Philippines Diliman, Philippines

    1 publications · 27 citations

    1

    h-index

  3. AS
    Atsushi Sugasaki

    Kyushu University, Japan

    1 publications · 43 citations

    1

    h-index

  4. AP
    Alexey Pereverzev

    University of Cologne, Germany

    1 publications · 14 citations

    1

    h-index

  5. JH
    J. Heath Wilder

    Tulane University, United States

    1 publications · 27 citations

    1

    h-index

1–5 of 76

Institutions

22

  1. University of Vienna

    Vienna, Austria

    1 h-index

    2 publications

    142 citations

  2. University of Minnesota

    Minneapolis, United States

    1 h-index

    7 publications

    504 citations

  3. Princeton University

    Princeton, United States

    1 h-index

    1 publications

    34 citations

  4. United States Bone and Joint Initiative

    Rosemont, United States

    1 h-index

    5 publications

    70 citations

  5. Albert Einstein College of Medicine

    Bronx, United States

    1 h-index

    1 publications

    25 citations

  6. Oak Ridge National Laboratory

    Oak Ridge, United States

    1 h-index

    3 publications

    81 citations

  7. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    1 h-index

    4 publications

    100 citations

  8. Scripps Research Institute

    San Diego, United States

    1 h-index

    6 publications

    294 citations

1–8 of 22

Venues

  1. Structure

    2 publications · 83 citations

    2

    h-index

  2. Nature Chemical Biology

    2 publications · 167 citations

    2

    h-index

  3. Journal of the American Chemical Society

    JACS · 1 publications · 35 citations

    1

    h-index

  4. 1

    h-index

  5. Journal of Biological Chemistry

    JBC · 1 publications · 25 citations

    1

    h-index

1–5