Concepedia

Positional Cloning

Positional Cloning is a gene mapping method that identifies and isolates a gene responsible for a specific trait or disease based solely on its chromosomal location, without prior knowledge of the gene’s function or expression.

934

Publications

156.9K

Citations

6K

Authors

1.2K

Institutions

Publications per year

2017–2026

70

Parents

Publications

934

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

, , +12

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene <i>BRCA1</i>

Yoshio Miki, Jeffrey Swensen, Donna Shattuck-Eidens et al. · Science · 1994 · 6.1K citations

, , +17

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

L. Arthur Campfield, Françoise J. Smith, Yves Guisez et al. · Science · 1995 · 3.3K citations

, , +17

Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.

Luda Diatchenko, Yun‐Fai Chris Lau, A. Patricia Campbell et al. · Proceedings of the National Academy of Sciences · 1996 · 3K citations

, , +13

Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene

Farida Latif, Kálmán Tory, James R. Gnarra et al. · Science · 1993 · 3K citations

, , +17

1–5 of 934

Authors

6K

  1. NE
    Newton E. Morton

    University of Hawaii System, United States

    11 publications · 987 citations

    10

    h-index

  2. FS
    Francis S. Collins

    National Human Genome Research Institute, United States

    9 publications · 4.3K citations

    9

    h-index

  3. AC
    Andrew Collins

    University of Southampton, United Kingdom

    9 publications · 906 citations

    9

    h-index

  4. NS
    Nils Stein

    Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK), Germany

    8 publications · 1.4K citations

    8

    h-index

  5. MC
    Mark C. Fishman

    Massachusetts General Hospital, United States

    7 publications · 891 citations

    7

    h-index

1–5 of 6K

Institutions

1.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    39 h-index

    45 publications

    27K citations

  2. Harvard University

    Cambridge, United States

    26 h-index

    30 publications

    5.9K citations

  3. Institute of Agrobiological Sciences

    Tsukuba, Japan

    22 h-index

    27 publications

    3.6K citations

  4. The University of Tokyo

    Tokyo, Japan

    21 h-index

    26 publications

    2.2K citations

  5. National Institutes of Health

    Bethesda, United States

    20 h-index

    28 publications

    9.4K citations

  6. Cornell University

    Ithaca, United States

    19 h-index

    21 publications

    5.8K citations

  7. University of Michigan

    Ann Arbor, United States

    19 h-index

    20 publications

    4.1K citations

  8. Kyoto University

    Kyoto, Japan

    17 h-index

    19 publications

    2K citations

1–8 of 1.2K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 86 publications · 21.9K citations

    70

    h-index

  2. Human Molecular Genetics

    45 publications · 7.8K citations

    41

    h-index

  3. The Plant Journal

    30 publications · 5.4K citations

    29

    h-index

  4. Science

    27 publications · 32.4K citations

    27

    h-index

  5. The Plant Cell

    27 publications · 11.9K citations

    27

    h-index

1–5