Pooled Screening Guide Design
Pooled Screening Guide Design is a methodological framework in functional genomics that enables the systematic construction of large-scale, diverse guide RNA libraries for simultaneous perturbation and screening of thousands of genetic elements within a single experiment.
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Increasing the performance of pooled CRISPR–Cas9 drop-out screening
Benedict C. S. Cross, Steffen Lawo, C Archer et al. · Scientific Reports · 2016 · 44 citations · Full text
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