Concepedia

Polyketide Precursor Biosynthesis

Polyketide Precursor Biosynthesis is a biosynthetic pathway that generates acyl-CoA-derived building blocks essential for polyketide assembly through sequential enzymatic condensation of small carbon units, distinguished by its role in producing structurally diverse metabolic precursors in secondary metabolism.

691

Publications

36K

Citations

2.4K

Authors

588

Institutions

Publications per year

2017–2026

98

Parents

Publications

691

Modular Organization of Genes Required for Complex Polyketide Biosynthesis

Stefano Donadio, Michael J. Staver, James B. McAlpine et al. · Science · 1991 · 909 citations

, , +17

Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.

Joseph P. Noel, Joseph M. Jez, M.E. Bowman et al. · Nature Structural Biology · 1999 · 673 citations

, , +16

Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

Jonathan Kennedy, Karine Auclair, Steven G. Kendrew et al. · Science · 1999 · 660 citations

, , +16

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

Jesús Cortés, Stephen Haydock, Gareth A. Roberts et al. · Nature · 1990 · 631 citations

, , +13

Engineered Biosynthesis of Novel Polyketides

Robert McDaniel, Susanne Ebert‐Khosla, David A. Hopwood et al. · Science · 1993 · 470 citations

, , +16

1–5 of 691

Authors

2.4K

  1. CK
    Chaitan Khosla

    Stanford University, United States

    48 publications · 3.4K citations

    35

    h-index

  2. PF
    Peter F. Leadlay

    University of Cambridge, United Kingdom

    28 publications · 1.9K citations

    19

    h-index

  3. JS
    James Staunton

    University of Cambridge, United Kingdom

    33 publications · 1.3K citations

    19

    h-index

  4. DE
    David E. Cane

    Brown University, United States

    20 publications · 1.4K citations

    19

    h-index

  5. BS
    Ben Shen

    University of Wisconsin–Madison, United States

    16 publications · 656 citations

    15

    h-index

1–5 of 2.4K

Institutions

588

  1. Stanford University

    Stanford, United States

    35 h-index

    157 publications

    11K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    24 h-index

    145 publications

    14.6K citations

  3. Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)

    Jena, Germany

    23 h-index

    119 publications

    5.7K citations

  4. University of Wisconsin–Madison

    Madison, United States

    20 h-index

    67 publications

    5.7K citations

  5. Brown University

    Providence, United States

    19 h-index

    68 publications

    5K citations

  6. The University of Tokyo

    Tokyo, Japan

    17 h-index

    66 publications

    4.3K citations

  7. University of California, Los Angeles

    Los Angeles, United States

    15 h-index

    59 publications

    4.5K citations

  8. University of Shizuoka

    Shizuoka, Japan

    15 h-index

    67 publications

    2.8K citations

1–8 of 588

Venues

  1. Journal of the American Chemical Society

    JACS · 47 publications · 2.8K citations

    37

    h-index

  2. Angewandte Chemie International Edition

    37 publications · 1.8K citations

    24

    h-index

  3. ChemBioChem

    29 publications · 965 citations

    22

    h-index

  4. Biochemistry

    22 publications · 980 citations

    19

    h-index

  5. Chemistry & Biology

    18 publications · 1.3K citations

    18

    h-index

1–5