Polygenic Inheritance

Polygenic Inheritance is a genetic inheritance pattern in which a phenotypic trait is influenced by the additive effects of multiple genes, each contributing a small and often indistinguishable effect, as opposed to the expression of a single gene with large phenotypic impact.

619

Publications

45K

Citations

3.5K

Authors

1.2K

Institutions

Publications per year

2017–2026

147

Parents

Human GeneticsQuantitative Genetics

Children

Common Variant ContributionComplex Trait ArchitectureCross-trait Genetic AssociationFamily-based Association StudiesGenetic Architecture Of Complex TraitsMissing HeritabilityPolygenic AdaptationPolygenic Score CalibrationRare Variant ContributionSelection On Polygenic Traits

Publications

619

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Manuel A. R. Ferreira · Nature · 2009 · 5K citations · Full text

Life Sciences, Genetics, Psychiatry +14

VII. Note on regression and inheritance in the case of two parents

Karl Pearson · Proceedings of the Royal Society of London · 1895 · 3.2K citations

Life Sciences, Biology, Genetics +14

Localization of the gene for familial adenomatous polyposis on chromosome 5

Walter F. Bodmer, Clyde Bailey, J. G. Bodmer et al. · Nature · 1987 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +11

Polygenic susceptibility to breast cancer and implications for prevention

Paul D.P. Pharoah, Antonis C. Antoniou, Martin Bobrow et al. · Nature Genetics · 2002 · 902 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation

Samuel A. Lambert, Laurent Gil, Simon Jupp et al. · Nature Genetics · 2021 · 744 citations · Full text

Life Sciences, Bioinformatics, Genetics +11

1–5 of 619

Authors

3.5K

RP
Robert Plomin
King's College London, United Kingdom
17 publications · 1.3K citations
17
h-index
KM
Kenneth Mather
John Innes Centre, United Kingdom
8 publications · 1.1K citations
8
h-index
KR
Kaili Rimfeld
King's College London, United Kingdom
8 publications · 559 citations
8
h-index
DI
Dorret I. Boomsma
Vrije Universiteit Amsterdam, Netherlands
8 publications · 1K citations
8
h-index
JN
James N. Thompson
University of Oklahoma, United States
7 publications · 129 citations
7
h-index

1–5 of 3.5K

Institutions

1.2K

1–8 of 1.2K

Venues

PubMed
Repository · 33 publications · 1.5K citations
19
h-index
Journal of Heredity
27 publications · 527 citations
16
h-index
Genetics
16 publications · 690 citations
14
h-index
Heredity
12 publications · 507 citations
12
h-index
The American Journal of Human Genetics
AJHG · 12 publications · 950 citations
12
h-index

1–5