Concepedia

Polycomb-repressed Domains

Polycomb-Repressed Domains is a genomic compartment characterized by the stable silencing of developmental genes through the targeted histone modifications mediated by Polycomb group proteins, distinguishing it from other chromatin domains by its unique enrichment of H3K27me3 and association with facultative heterochromatin.

26

Publications

3.9K

Citations

189

Authors

85

Institutions

Publications per year

2017–2026

10

Variants

Polycomb-associated Domains

Parents

Publications

26

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

Neil P. Blackledge, Anca M. Farcas, Takashi Kondo et al. · Cell · 2014 · 760 citations · Full text

, , +17

Cloning, expression and chromosome locations of the human DNMT3 gene family

Shaoping Xie, Zhenjuan Wang, Masaki Okano et al. · Gene · 1999 · 421 citations

, , +13

Mapping polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin

Valerio Orlando, Renato Paro · Cell · 1993 · 360 citations

, , +14

Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation

Sharmistha Kundu, Fei Ji, Hongjae Sunwoo et al. · Molecular Cell · 2017 · 348 citations · Full text

, , +12

PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos

Mareike Puschendorf, Rémi Terranova, Erwin Boutsma et al. · Nature Genetics · 2008 · 322 citations

, , +14

1–5 of 26

Authors

189

  1. RP
    Renato Paro

    Heidelberg University, Germany

    3 publications · 729 citations

    3

    h-index

  2. RE
    Robert E. Kingston

    Massachusetts General Hospital, United States

    2 publications · 360 citations

    2

    h-index

  3. KJ
    Kirsty Jamieson

    University of Oregon, United States

    2 publications · 277 citations

    2

    h-index

  4. HS
    Hongjae Sunwoo

    Massachusetts General Hospital, United States

    2 publications · 438 citations

    2

    h-index

  5. LR
    Leonie Ringrose

    Institute of Molecular Biotechnology, Austria

    2 publications · 369 citations

    2

    h-index

1–5 of 189

Institutions

85

  1. Harvard University

    Cambridge, United States

    6 h-index

    21 publications

    5.2K citations

  2. Massachusetts General Hospital

    Boston, United States

    4 h-index

    18 publications

    4.3K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    6 publications

    1.5K citations

  4. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    2 h-index

    5 publications

    752 citations

  5. University of Oregon

    Eugene, United States

    2 h-index

    9 publications

    1.2K citations

  6. University of Massachusetts Chan Medical School

    Worcester, United States

    2 h-index

    4 publications

    738 citations

  7. Heidelberg University

    Heidelberg, Germany

    2 h-index

    4 publications

    1.3K citations

  8. Fred Hutch Cancer Center

    Seattle, United States

    2 h-index

    8 publications

    568 citations

1–8 of 85

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 490 citations

    3

    h-index

  2. Nature Genetics

    2 publications · 414 citations

    2

    h-index

  3. Cell

    2 publications · 1.1K citations

    2

    h-index

  4. PubMed

    Repository · 2 publications · 41 citations

    2

    h-index

  5. Molecular Cell

    2 publications · 453 citations

    2

    h-index

1–5