Concepedia

Polyadenylation-linked Termination

Polyadenylation-Linked Termination is a transcription termination mechanism in eukaryotic RNA polymerase II-mediated gene expression wherein the cleavage and polyadenylation of the pre-mRNA transcript at the 3′ untranslated region directly trigger the dissociation of the transcription machinery from the DNA template.

31

Publications

2.6K

Citations

145

Authors

57

Institutions

Publications per year

2017–2026

8

Variants

Polyadenylation-linked Transcription Termination

Parents

Publications

31

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene.

John S. Logan, Erik Falck-Pedersen, James Darnell et al. · Proceedings of the National Academy of Sciences · 1987 · 265 citations · Full text

, , +17

Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors

Yung-Chia Ariel Chen, Evelyn Stuwe, Yicheng Luo et al. · Molecular Cell · 2016 · 164 citations · Full text

, , +14

Evolutionarily Conserved Interaction between CstF-64 and PC4 Links Transcription, Polyadenylation, and Termination

Olga Calvo, James L. Manley · Molecular Cell · 2001 · 161 citations · Full text

, , +10

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

Lea H. Gregersen, Richard Mitter, Alejandro P. Ugalde et al. · Cell · 2019 · 155 citations · Full text

, , +17

Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination

Kinga Kamieniarz-Gdula, Michał R. Gdula, Karin Panser et al. · Molecular Cell · 2019 · 151 citations · Full text

, , +17

1–5 of 31

Authors

145

  1. JL
    Jeffry L. Corden

    Johns Hopkins University, United States

    3 publications · 258 citations

    3

    h-index

  2. CM
    Claire Moore

    Tufts University, United States

    1 publications · 61 citations

    2

    h-index

  3. NB
    Niranjan B. Pandey

    Johns Hopkins University, United States

    2 publications · 60 citations

    2

    h-index

  4. NC
    Nunta Chodchoy

    Florida State University, United States

    2 publications · 60 citations

    2

    h-index

  5. WF
    William F. Marzluff

    University of North Carolina at Chapel Hill, United States

    2 publications · 60 citations

    2

    h-index

1–5 of 145

Institutions

57

  1. Johns Hopkins University

    Baltimore, United States

    3 h-index

    11 publications

    1.1K citations

  2. University of Toronto

    Toronto, Canada

    3 h-index

    8 publications

    1.1K citations

  3. Johns Hopkins Medicine

    Baltimore, United States

    3 h-index

    11 publications

    1.1K citations

  4. Florida State University

    Tallahassee, United States

    2 h-index

    6 publications

    180 citations

  5. Ontario Institute for Cancer Research

    Toronto, Canada

    2 h-index

    2 publications

    182 citations

  6. Tufts University

    Medford, United States

    2 h-index

    2 publications

    122 citations

  7. University of Oxford

    Oxford, United Kingdom

    2 h-index

    9 publications

    1.4K citations

  8. University of Basel

    Basel, Switzerland

    2 h-index

    9 publications

    1.2K citations

1–8 of 57

Venues

  1. Molecular Cell

    5 publications · 740 citations

    5

    h-index

  2. The EMBO Journal

    5 publications · 370 citations

    5

    h-index

  3. Cell

    4 publications · 391 citations

    4

    h-index

  4. Molecular and Cellular Biology

    MCB · 4 publications · 220 citations

    4

    h-index

  5. RNA

    3 publications · 209 citations

    3

    h-index

1–5