Concepedia

Polyadenylation During Development

Polyadenylation During Development is a biological regulatory mechanism—specifically, the temporally and spatially controlled addition of poly(A) tails to messenger RNA molecules—that modulates mRNA stability, localization, and translational efficiency in a developmental stage-specific and tissue-specific manner.

180

Publications

13.6K

Citations

565

Authors

214

Institutions

Publications per year

2017–2026

14

Parents

Publications

180

The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation

Philip Olsen, Victor Ambros · Developmental Biology · 1999 · 1.2K citations

, , +17

Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

Zhe Ji, Ju Youn Lee, Zhenhua Pan et al. · Proceedings of the National Academy of Sciences · 2009 · 617 citations · Full text

, , +17

Quantitative changes in total RNA, total poly(A), and ribosomes in early mouse embryos

Lajos Pikó, Kerry B. Clegg · Developmental Biology · 1982 · 375 citations

, , +14

Extensive alternative polyadenylation during zebrafish development

Igor Ulitsky, Alena Shkumatava, Calvin H. Jan et al. · Genome Research · 2012 · 345 citations · Full text

, , +17

The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation.

Michael Sheets, Catherine A. Fox, Tim Hunt et al. · Genes & Development · 1994 · 328 citations · Full text

, , +17

1–5 of 180

Authors

565

  1. JD
    Joel D. Richter

    University of Massachusetts Chan Medical School, United States

    16 publications · 1.4K citations

    15

    h-index

  2. MW
    Marvin Wickens

    University of Wisconsin–Madison, United States

    11 publications · 1.6K citations

    11

    h-index

  3. MB
    Mark B. Dworkin

    Columbia University, United States

    4 publications · 248 citations

    4

    h-index

  4. EH
    Eric H. Davidson

    California Institute of Technology, United States

    4 publications · 329 citations

    4

    h-index

  5. RJ
    Roy J. Britten

    California Institute of Technology, United States

    4 publications · 329 citations

    4

    h-index

1–5 of 565

Institutions

214

  1. University of Wisconsin–Madison

    Madison, United States

    13 h-index

    35 publications

    5.2K citations

  2. University of California, Berkeley

    Berkeley, United States

    9 h-index

    20 publications

    1.9K citations

  3. California Institute of Technology

    Pasadena, United States

    8 h-index

    25 publications

    2.9K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    30 publications

    2K citations

  5. Fox Chase Cancer Center

    Philadelphia, United States

    6 h-index

    13 publications

    1.2K citations

  6. National Institutes of Health

    Bethesda, United States

    5 h-index

    9 publications

    1.1K citations

  7. University of Washington

    Seattle, United States

    5 h-index

    15 publications

    914 citations

  8. Université de Rennes

    Rennes, France

    4 h-index

    16 publications

    963 citations

1–8 of 214

Venues

  1. Developmental Biology

    26 publications · 3.1K citations

    21

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 17 publications · 1.7K citations

    17

    h-index

  3. Molecular and Cellular Biology

    MCB · 17 publications · 855 citations

    17

    h-index

  4. Genes & Development

    7 publications · 1.5K citations

    7

    h-index

  5. The EMBO Journal

    6 publications · 781 citations

    6

    h-index

1–5