Concepedia

Polyadenylation Complex Assembly

Polyadenylation Complex Assembly is a molecular machinery recruitment process in which a defined set of protein factors and RNA elements coalesce at the pre-mRNA 3′ end to form a functional ribonucleoprotein complex that mediates site-specific cleavage and polyadenylation.

38

Publications

3.3K

Citations

103

Authors

53

Institutions

Publications per year

2017–2026

3

Parents

Publications

38

RNA polymerase II is an essential mRNA polyadenylation factor

Yutaka Hirose, James L. Manley · Nature · 1998 · 356 citations

, , +14

Symplekin and xGLD-2 Are Required for CPEB-Mediated Cytoplasmic Polyadenylation

Daron Barnard, Kevin Ryan, James L. Manley et al. · Cell · 2004 · 331 citations · Full text

, , +12

Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes

Xiaofeng Fang, Liang Wang, Ryo Ishikawa et al. · Nature · 2019 · 325 citations · Full text

, , +13

Complex Protein Interactions within the Human Polyadenylation Machinery Identify a Novel Component

Yoshio Takagaki, James L. Manley · Molecular and Cellular Biology · 2000 · 244 citations

, , +17

Phosphorylation of CPEB by Eg2 Mediates the Recruitment of CPSF into an Active Cytoplasmic Polyadenylation Complex

Raúl Méndez, Kannenganti G.K. Murthy, Kevin Ryan et al. · Molecular Cell · 2000 · 242 citations · Full text

, , +10

1–5 of 38

Authors

103

  1. JL
    James L. Manley

    Columbia University, United States

    6 publications · 1.4K citations

    6

    h-index

  2. HS
    Hagit Skolnik-David

    Weizmann Institute of Science, Israel

    3 publications · 146 citations

    3

    h-index

  3. CM
    Claire Moore

    Tufts University, United States

    3 publications · 146 citations

    3

    h-index

  4. PA
    Phillip A. Sharp

    Massachusetts Institute of Technology, United States

    3 publications · 146 citations

    3

    h-index

  5. WR
    William R. Jeffery

    University of Maryland, College Park, United States

    2 publications · 89 citations

    2

    h-index

1–5 of 103

Institutions

53

  1. Columbia University

    New York, United States

    6 h-index

    15 publications

    3.2K citations

  2. Rutgers, The State University of New Jersey

    New Brunswick, United States

    3 h-index

    6 publications

    287 citations

  3. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    3 h-index

    8 publications

    849 citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    9 publications

    438 citations

  5. Center for Cancer Research

    Bethesda, United States

    2 h-index

    6 publications

    183 citations

  6. University of Colorado Denver

    Denver, United States

    2 h-index

    4 publications

    110 citations

  7. National Jewish Health

    Denver, United States

    2 h-index

    4 publications

    110 citations

  8. University of Massachusetts Chan Medical School

    Worcester, United States

    2 h-index

    4 publications

    1.1K citations

1–8 of 53

Venues

  1. Molecular and Cellular Biology

    MCB · 8 publications · 459 citations

    8

    h-index

  2. Molecular Cell

    3 publications · 461 citations

    3

    h-index

  3. Nature

    3 publications · 820 citations

    3

    h-index

  4. Journal of Molecular Biology

    JMB · 3 publications · 228 citations

    3

    h-index

  5. Genes & Development

    2 publications · 278 citations

    2

    h-index

1–5