Concepedia

Plasmid Backbone Engineering

Plasmid Backbone Engineering is a methodological approach within genetic vector design that involves the targeted modification of non-coding plasmid elements—such as origin of replication, antibiotic resistance genes, and regulatory sequences—to optimize episomal stability, copy number, and compatibility for efficient and sustained plasmid DNA delivery in host cells.

28

Publications

1.9K

Citations

171

Authors

64

Institutions

Publications per year

2017–2026

9

Parents

Publications

28

[19] In Vitro packaging of λ and cosmid DNA

Barbara Höhn · Methods in enzymology on CD-ROM/Methods in enzymology · 1979 · 532 citations

, , +14

Complete sequence of the IncPβ plasmid R751: implications for evolution and organisation of the IncP backbone

Peter B. Thorsted, Donia Macartney‐Coxson, Parveen Akhtar et al. · Journal of Molecular Biology · 1998 · 217 citations

, , +16

A Human T-Cell Leukemia Virus Type 1 Regulatory Element Enhances the Immunogenicity of Human Immunodeficiency Virus Type 1 DNA Vaccines in Mice and Nonhuman Primates

Dan H. Barouch, Zhi-Yong Yang, Wing-Pui Kong et al. · Journal of Virology · 2005 · 166 citations · Full text

, , +17

Recombinational construction in <i>Escherichia coli</i> of infectious adenoviral genomes

Joël Crouzet, Laurent Naudin, Cécile Orsini et al. · Proceedings of the National Academy of Sciences · 1997 · 115 citations · Full text

, , +15

Molecular Toolkit for Gene Expression Control and Genome Modification in<i>Rhodococcus opacus</i>PD630

Drew M. DeLorenzo, Austin G. Rottinghaus, William R. Henson et al. · ACS Synthetic Biology · 2018 · 88 citations · Full text

, , +17

1–5 of 28

Authors

171

  1. GA
    Gabriel A. Monteiro

    Instituto Superior Técnico, Portugal

    1 publications · 16 citations

    1

    h-index

  2. LD
    Liuxin Dong

    National Institute for Viral Disease Control and Prevention, China

    1 publications · 25 citations

    1

    h-index

  3. ZS
    Zhenying Shi

    Center for Excellence in Molecular Plant Sciences, China

    1 publications · 51 citations

    1

    h-index

  4. AG
    Austin G. Rottinghaus

    Washington University in St. Louis, United States

    1 publications · 88 citations

    1

    h-index

  5. DR
    Deborah R. Gill

    University of Oxford, United Kingdom

    1 publications · 18 citations

    1

    h-index

1–5 of 171

Institutions

64

  1. Shandong University

    Jinan, China

    2 h-index

    6 publications

    135 citations

  2. University of Vienna

    Vienna, Austria

    2 h-index

    6 publications

    334 citations

  3. LMU Klinikum

    Munich, Germany

    1 h-index

    1 publications

    84 citations

  4. DECHEMA-Forschungsinstitut

    Frankfurt am Main, Germany

    1 h-index

    4 publications

    172 citations

  5. University of Birmingham

    Birmingham, United Kingdom

    1 h-index

    8 publications

    1.7K citations

  6. Cystic Fibrosis Trust

    London, United Kingdom

    1 h-index

    7 publications

    126 citations

  7. Society for Chemical Engineering and Biotechnology

    Frankfurt am Main, Germany

    1 h-index

    5 publications

    215 citations

  8. Institute for Biotechnology and Bioengineering

    Lisbon, Portugal

    1 h-index

    3 publications

    48 citations

1–8 of 64

Venues

  1. ACS Synthetic Biology

    3 publications · 131 citations

    3

    h-index

  2. Methods in enzymology on CD-ROM/Methods in enzymology

    Book series · 2 publications · 546 citations

    2

    h-index

  3. Human Gene Therapy

    1 publications · 13 citations

    1

    h-index

  4. The FASEB Journal

    1 publications · 18 citations

    1

    h-index

  5. Journal of Molecular Biology

    JMB · 1 publications · 217 citations

    1

    h-index

1–5