Concepedia

Piwi-interacting Rna Function

Piwi-Interacting RNA Function is a molecular regulatory mechanism defined as a noncoding RNA function that specifically mediates transcriptional and post-transcriptional gene silencing through sequence-directed interactions with Piwi-clade Argonaute proteins, primarily in germline and stem cells.

531

Publications

52.8K

Citations

2.9K

Authors

827

Institutions

Publications per year

2017–2026

247

Parents

Publications

531

A germline-specific class of small RNAs binds mammalian Piwi proteins

Angélique Girard, Ravi Sachidanandam, Gregory J. Hannon et al. · Nature · 2006 · 1.8K citations

, , +11

Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity

Ji‐Joon Song, Stephanie K. Smith, Gregory J. Hannon et al. · Science · 2004 · 1.5K citations

, , +16

A Slicer-Mediated Mechanism for Repeat-Associated siRNA 5' End Formation in <i>Drosophila</i>

Lalith Gunawardane, Kuniaki Saito, Kazumichi M. Nishida et al. · Science · 2007 · 1.2K citations

, , +14

A Role for Piwi and piRNAs in Germ Cell Maintenance and Transposon Silencing in Zebrafish

Saskia Houwing, Leonie M. Kamminga, Eugène Berezikov et al. · Cell · 2007 · 1.2K citations · Full text

, , +14

Developmentally Regulated piRNA Clusters Implicate MILI in Transposon Control

Alexei A. Aravin, Ravi Sachidanandam, Angélique Girard et al. · Science · 2007 · 1K citations

, , +12

1–5 of 531

Authors

2.9K

  1. MC
    Mikiko C. Siomi

    The University of Tokyo, Japan

    24 publications · 4.6K citations

    21

    h-index

  2. HS
    Haruhiko Siomi

    Keio University, Japan

    22 publications · 4.6K citations

    21

    h-index

  3. GJ
    Gregory J. Hannon

    Cold Spring Harbor Laboratory, United States

    19 publications · 7.6K citations

    19

    h-index

  4. RS
    Ravi Sachidanandam

    Icahn School of Medicine at Mount Sinai, United States

    17 publications · 5.3K citations

    17

    h-index

  5. HL
    Haifan Lin

    Yale University, United States

    16 publications · 3.5K citations

    16

    h-index

1–5 of 2.9K

Institutions

827

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    30 h-index

    103 publications

    11.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    153 publications

    11.4K citations

  3. Yale University

    New Haven, United States

    20 h-index

    60 publications

    6.7K citations

  4. Chinese Academy of Sciences

    Beijing, China

    19 h-index

    109 publications

    12.9K citations

  5. Cold Spring Harbor Laboratory

    Cold Spring Harbor, United States

    19 h-index

    74 publications

    30.6K citations

  6. The University of Tokyo

    Tokyo, Japan

    18 h-index

    121 publications

    9.1K citations

  7. Keio University

    Tokyo, Japan

    17 h-index

    63 publications

    7.2K citations

  8. University of Cambridge

    Cambridge, United Kingdom

    17 h-index

    85 publications

    10.5K citations

1–8 of 827

Venues

  1. Nucleic Acids Research

    30 publications · 3.1K citations

    27

    h-index

  2. RNA

    32 publications · 2.7K citations

    24

    h-index

  3. Genes & Development

    24 publications · 5.3K citations

    24

    h-index

  4. Cell Reports

    20 publications · 1.4K citations

    20

    h-index

  5. PLoS Genetics

    20 publications · 1.6K citations

    19

    h-index

1–5