Pipeline engineering is a research domain concerned with the systematic design, analysis, and optimization of sequential processes and interconnected systems that facilitate the transformation, transfer, and utilization of energy or materials. Within the context of energy generation systems, such as those harnessing nuclear reactions, it investigates the efficient and controlled progression through distinct conversion stages, from initial energy release (e.g., nuclear fission or fusion) to subsequent forms (e.g., thermal, mechanical, electrical), emphasizing flow dynamics, system integration, and operational efficacy across the entire chain.