Concepedia

Phospholipid Flippases

Phospholipid Flippase is an ATP-dependent transmembrane enzyme that catalyzes the selective inward translocation of phosphatidylserine and other aminophospholipids from the outer to the inner leaflet of the plasma membrane, thereby maintaining membrane asymmetry.

171

Publications

10.4K

Citations

621

Authors

215

Institutions

Publications per year

2017–2026

53

Variants

P4-atpases

Parents

Publications

171

Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

Katsumori Segawa, Sachiko Kurata, Yuichi Yanagihashi et al. · Science · 2014 · 528 citations

, , +17

ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity

Coen C. Paulusma, Dineke E. Folmer, Kam S. Ho‐Mok et al. · Hepatology · 2007 · 245 citations · Full text

, , +16

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

Coen C. Paulusma, Annemiek Groen, Cindy Kunne et al. · Hepatology · 2006 · 231 citations · Full text

, , +17

ATPase Activity of the MsbA Lipid Flippase of Escherichia coli

William T. Doerrler, Christian R.H. Raetz · Journal of Biological Chemistry · 2002 · 221 citations · Full text

, , +17

Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Masahiro Hiraizumi, Keitaro Yamashita, Tomohiro Nishizawa et al. · Science · 2019 · 194 citations

, , +17

1–5 of 171

Authors

621

  1. RS
    Robert S. Molday

    University of British Columbia, Canada

    14 publications · 952 citations

    13

    h-index

  2. TG
    Thomas Günther Pomorski

    University of Copenhagen, Denmark

    13 publications · 739 citations

    13

    h-index

  3. TR
    Todd R. Graham

    Vanderbilt University, United States

    13 publications · 968 citations

    12

    h-index

  4. KS
    Katsumori Segawa

    The University of Osaka, Japan

    10 publications · 1.2K citations

    10

    h-index

  5. KT
    Kazuma Tanaka

    Hokkaido University, Japan

    10 publications · 335 citations

    10

    h-index

1–5 of 621

Institutions

215

  1. University of British Columbia

    Vancouver, Canada

    16 h-index

    41 publications

    2.8K citations

  2. Vanderbilt University

    Nashville, United States

    12 h-index

    39 publications

    2.9K citations

  3. University of Copenhagen

    Copenhagen, Denmark

    11 h-index

    60 publications

    2.8K citations

  4. Hokkaido University

    Sapporo, Japan

    10 h-index

    45 publications

    1.4K citations

  5. Kyoto University

    Kyoto, Japan

    10 h-index

    59 publications

    6.7K citations

  6. Humboldt-Universität zu Berlin

    Berlin, Germany

    8 h-index

    28 publications

    1.7K citations

  7. The University of Osaka

    Osaka, Japan

    8 h-index

    25 publications

    1.6K citations

  8. Aarhus University

    Aarhus, Denmark

    8 h-index

    27 publications

    1K citations

1–8 of 215

Venues

  1. Journal of Biological Chemistry

    JBC · 29 publications · 2.3K citations

    26

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 1K citations

    13

    h-index

  3. Molecular Biology of the Cell

    MBC · 11 publications · 723 citations

    11

    h-index

  4. Biochemistry

    10 publications · 729 citations

    10

    h-index

  5. 6

    h-index

1–5