Concepedia

Pharmacophore-based Database Screening

Pharmacophore-Based Database Screening is a computational drug discovery method that identifies potential lead compounds by searching chemical databases for molecules that match a predefined three-dimensional arrangement of structural features essential for biological activity.

195

Publications

12.4K

Citations

1.1K

Authors

362

Institutions

Publications per year

2017–2026

72

Parents

Publications

195

PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database

Xia Wang, Yihang Shen, Shiwei Wang et al. · Nucleic Acids Research · 2017 · 1.6K citations · Full text

, , +11

Simple Selection Criteria for Drug-like Chemical Matter

Ingo Muegge, Sarah L. Heald, David R. Brittelli · Journal of Medicinal Chemistry · 2001 · 1.3K citations

, , +11

PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results

Steven L. Dixon, Alexander M. Smondyrev, Eric H. Knoll et al. · Journal of Computer-Aided Molecular Design · 2006 · 1.2K citations

, , +17

PHASE: A Novel Approach to Pharmacophore Modeling and 3D Database Searching

Steven L. Dixon, Alexander M. Smondyrev, Shashidhar N. Rao · Chemical Biology & Drug Design · 2006 · 689 citations · Full text

, , +17

ZINCPharmer: pharmacophore search of the ZINC database

David Ryan Koes, Carlos J. Camacho · Nucleic Acids Research · 2012 · 440 citations · Full text

, , +17

1–5 of 195

Authors

1.1K

  1. KW
    Keun Woo Lee

    Gyeongsang National University, South Korea

    10 publications · 359 citations

    10

    h-index

  2. TL
    Thierry Langer

    Universität Innsbruck, Austria

    7 publications · 351 citations

    7

    h-index

  3. SR
    Shailima Rampogu

    Gyeongsang National University, South Korea

    6 publications · 142 citations

    6

    h-index

  4. CP
    Chanin Park

    Gyeongsang National University, South Korea

    5 publications · 125 citations

    5

    h-index

  5. DS
    Daniela Schuster

    Universität Innsbruck, Austria

    5 publications · 168 citations

    5

    h-index

1–5 of 1.1K

Institutions

362

  1. Gyeongsang National University

    Jinju-si, South Korea

    11 h-index

    58 publications

    2.1K citations

  2. Universität Innsbruck

    Innsbruck, Austria

    10 h-index

    42 publications

    1.9K citations

  3. Sichuan University

    Chengdu, China

    5 h-index

    35 publications

    1.3K citations

  4. National Cancer Institute

    Bethesda, United States

    5 h-index

    20 publications

    1.5K citations

  5. Alagappa University

    Karaikudi, India

    4 h-index

    8 publications

    152 citations

  6. National Institutes of Health

    Bethesda, United States

    4 h-index

    22 publications

    1.4K citations

  7. University of Pittsburgh

    Pittsburgh, United States

    4 h-index

    15 publications

    2.3K citations

  8. Zhejiang University

    Hangzhou, China

    4 h-index

    29 publications

    1.2K citations

1–8 of 362

Venues

  1. Journal of Medicinal Chemistry

    20 publications · 2.3K citations

    19

    h-index

  2. Bioorganic & Medicinal Chemistry Letters

    10 publications · 245 citations

    10

    h-index

  3. Journal of Biomolecular Structure and Dynamics

    10 publications · 270 citations

    10

    h-index

  4. Journal of Chemical Information and Modeling

    JCIM · 9 publications · 409 citations

    9

    h-index

  5. International Journal of Molecular Sciences

    IJMS · 7 publications · 206 citations

    7

    h-index

1–5