Concepedia

Pharmacodynamic Interaction Analysis

Pharmacodynamic Interaction Analysis is a pharmacological assessment method that characterizes the functional interactions between drug compounds in combination therapy by evaluating their combined effects on biological targets, distinguishing it from pharmacokinetic analyses by focusing on the magnitude and nature of therapeutic or toxic responses resulting from drug co-administration.

133

Publications

6.9K

Citations

651

Authors

255

Institutions

Publications per year

2017–2026

20

Parents

Publications

133

Pharmacodynamic Interaction between Propofol and Remifentanil Regarding Hypnosis, Tolerance of Laryngoscopy, Bispectral Index, and Electroencephalographic Approximate Entropy

Thomas Bouillon, Jörgen Bruhn, Lucian Radulescu et al. · Anesthesiology · 2004 · 369 citations · Full text

, , +16

The interaction index: a measure of drug synergism

Ronald J. Tallarida · Pain · 2002 · 287 citations

, , +15

Pharmacokinetic and Pharmacodynamic Consequences of Metabolism‐Based Drug Interactions with Alprazolam, Midazolam, and Triazolam

Rae Yuan, David A. Flockhart, John Dikran Balian · The Journal of Clinical Pharmacology · 1999 · 274 citations

, , +13

Analysis of Drug Interactions

Irene V. Bijnsdorp, Elisa Giovannetti, Godefridus J. Peters · Methods in molecular biology · 2011 · 249 citations

, , +12

The Efficacy of Valproate‐Lamotrigine Comedication in Refractory Complex Partial Seizures: Evidence for a Pharmacodynamic Interaction

Francesco Pisani, G. Oteri, Marco Russo et al. · Epilepsia · 1999 · 249 citations

, , +15

1–5 of 133

Authors

651

  1. MD
    Meindert Danhof

    Leiden University, Netherlands

    5 publications · 178 citations

    5

    h-index

  2. TB
    Thomas Bouillon

    University of Bonn, Germany

    4 publications · 453 citations

    4

    h-index

  3. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    3 publications · 84 citations

    3

    h-index

  4. TK
    Teddy Kosoglou

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    3 publications · 93 citations

    3

    h-index

  5. JB
    Jörgen Bruhn

    Radboud University Nijmegen, Netherlands

    3 publications · 397 citations

    3

    h-index

1–5 of 651

Institutions

255

  1. Centre for Human Drug Research

    Leiden, The Netherlands

    5 h-index

    10 publications

    223 citations

  2. University of Bonn

    Bonn, Germany

    4 h-index

    12 publications

    527 citations

  3. Leiden University

    Leiden, The Netherlands

    3 h-index

    9 publications

    402 citations

  4. Temple University

    Philadelphia, United States

    3 h-index

    3 publications

    580 citations

  5. University of Utah

    Salt Lake City, United States

    3 h-index

    4 publications

    165 citations

  6. Stichting Epilepsie Instellingen Nederland

    Heemstede, Netherlands

    3 h-index

    7 publications

    180 citations

  7. UNSW Sydney

    Sydney, Australia

    3 h-index

    12 publications

    1.1K citations

  8. Novartis (Switzerland)

    Basel, Switzerland

    3 h-index

    10 publications

    330 citations

1–8 of 255

Venues

  1. British Journal of Clinical Pharmacology

    BJCP · 9 publications · 236 citations

    9

    h-index

  2. The Journal of Clinical Pharmacology

    6 publications · 453 citations

    6

    h-index

  3. Clinical Pharmacology & Therapeutics

    CPT · 5 publications · 204 citations

    5

    h-index

  4. European Journal of Clinical Pharmacology

    5 publications · 124 citations

    5

    h-index

  5. Anesthesiology

    5 publications · 834 citations

    5

    h-index

1–5