Concepedia

Ph-solubility Profiling

pH-Solubility Profiling is a preformulation screening method that characterizes the solubility of a drug substance as a function of pH to establish its ionization behavior and dissolution characteristics across physiologically relevant pH conditions.

96

Publications

4.4K

Citations

378

Authors

133

Institutions

Publications per year

2017–2026

21

Parents

Publications

96

Prevalence of Acid-Reducing Agents (ARA) in Cancer Populations and ARA Drug–Drug Interaction Potential for Molecular Targeted Agents in Clinical Development

Gillian S. Smelick, Timothy P. Heffron, Laura Chu et al. · Molecular Pharmaceutics · 2013 · 188 citations

, , +14

pH-Dependent Solubility and Dissolution Behavior of Carvedilol—Case Example of a Weakly Basic BCS Class II Drug

Rania Hamed, Areeg Awadallah, Suhair Sunoqrot et al. · AAPS PharmSciTech · 2015 · 180 citations · Full text

, , +16

Determination of calcium salt solubility with changes in pH and PCO2, simulating varying gastrointestinal environments

Sandra Goss, Karen A Lemons, Jane E. Kerstetter et al. · Journal of Pharmacy and Pharmacology · 2007 · 149 citations · Full text

, , +17

Co-solvent solubilization of some poorly-soluble antidiabetic drugs

Neelam Seedher, Mamta Kanojia · Pharmaceutical Development and Technology · 2009 · 136 citations

, , +17

Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship

Gergely Völgyi, Edit Baka, Karl Box et al. · Analytica Chimica Acta · 2010 · 118 citations

, , +14

1–5 of 96

Authors

378

  1. AA
    Alex Avdeef

    Sumitomo Dainippon Pharma (United States), United States

    5 publications · 139 citations

    5

    h-index

  2. AT
    Abu T.M. Serajuddin

    St. John's University, United States

    4 publications · 163 citations

    4

    h-index

  3. CR
    Clara Ràfols

    Universitat de Barcelona, Spain

    3 publications · 118 citations

    3

    h-index

  4. WH
    William H. Streng

    University of Kansas, United States

    3 publications · 113 citations

    3

    h-index

  5. EB
    Elisabeth Bosch

    Universitat de Barcelona, Spain

    3 publications · 118 citations

    3

    h-index

1–5 of 378

Institutions

133

  1. Universitat de Barcelona

    Barcelona, Spain

    3 h-index

    11 publications

    449 citations

  2. Tabriz University of Medical Sciences

    Tabriz, Iran

    3 h-index

    15 publications

    400 citations

  3. Aston University

    Birmingham, United Kingdom

    2 h-index

    4 publications

    390 citations

  4. TU Dortmund University

    Dortmund, Germany

    2 h-index

    6 publications

    350 citations

  5. Hokkaido University

    Sapporo, Japan

    2 h-index

    8 publications

    162 citations

  6. Semmelweis University

    Budapest, Hungary

    2 h-index

    6 publications

    390 citations

  7. St. John's University

    New York, United States

    2 h-index

    5 publications

    150 citations

  8. Pfizer (United States)

    New York, United States

    2 h-index

    8 publications

    191 citations

1–8 of 133

Venues

  1. Journal of Pharmaceutical Sciences

    9 publications · 438 citations

    9

    h-index

  2. Pharmaceutical Development and Technology

    6 publications · 297 citations

    6

    h-index

  3. International Journal of Pharmaceutics

    5 publications · 152 citations

    5

    h-index

  4. European Journal of Pharmaceutical Sciences

    5 publications · 229 citations

    5

    h-index

  5. Molecular Pharmaceutics

    4 publications · 309 citations

    4

    h-index

1–5