Concepedia

Ph-dependent Partitioning

pH-Dependent Partitioning is a partition coefficient model that characterizes the distribution of ionizable compounds between immiscible phases as a function of pH, distinguishing itself from general partitioning models by explicitly accounting for pH-induced changes in molecular ionization state.

98

Publications

5.4K

Citations

307

Authors

142

Institutions

Publications per year

2017–2026

19

Parents

Publications

98

pH-Dependent partitioning in room temperature ionic liquids

Ann E. Visser, Richard P. Swatloski, Robin D. Rogers · Green Chemistry · 2000 · 279 citations

, , +7

Partitioning in Aqueous Two-Phase Systems: Fundamentals, Applications and Trends

António L. Grilo, M. Raquel Aires‐Barros, Ana M. Azevedo · Separation and Purification Reviews · 2014 · 269 citations

, , +17

pH-Metric log P. II: Refinement of Partition Coefficients and Ionization Constants of Multiprotic Substances

Alex Avdeef · Journal of Pharmaceutical Sciences · 1993 · 225 citations

, , +14

Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods

Markus Fridén, Fredrik Bergström, Hong Wan et al. · Drug Metabolism and Disposition · 2010 · 183 citations

, , +17

pH‐Metric log P. Part 1. Difference Plots for Determining Ion‐Pair Octanol‐Water Partition Coefficients of Multiprotic Substances

Alex Avdeef · Quantitative Structure-Activity Relationships · 1992 · 173 citations

, , +12

1–5 of 98

Authors

307

  1. MH
    Michael H. Abraham

    University College London, United Kingdom

    4 publications · 291 citations

    4

    h-index

  2. HH
    Hubert H. Girault

    École Polytechnique Fédérale de Lausanne, Switzerland

    3 publications · 343 citations

    3

    h-index

  3. WE
    William E. Acree

    University of North Texas, United States

    3 publications · 227 citations

    3

    h-index

  4. BT
    Bernard Testa

    University of Lausanne, Switzerland

    3 publications · 343 citations

    3

    h-index

  5. FR
    Frédéric Reymond

    École Polytechnique Fédérale de Lausanne, Switzerland

    3 publications · 343 citations

    3

    h-index

1–5 of 307

Institutions

142

  1. University College London

    London, United Kingdom

    4 h-index

    5 publications

    355 citations

  2. East Sussex County Council

    Lewes, United Kingdom

    3 h-index

    4 publications

    646 citations

  3. École Polytechnique Fédérale de Lausanne

    Lausanne, Switzerland

    3 h-index

    10 publications

    1.2K citations

  4. University of Lausanne

    Lausanne, Switzerland

    3 h-index

    11 publications

    1.3K citations

  5. University of North Texas

    Denton, United States

    3 h-index

    3 publications

    227 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    3 publications

    136 citations

  7. University of Georgia

    Athens, United States

    2 h-index

    2 publications

    21 citations

  8. University of Virginia

    Charlottesville, United States

    2 h-index

    4 publications

    54 citations

1–8 of 142

Venues

  1. Environmental Science & Technology

    6 publications · 366 citations

    6

    h-index

  2. Journal of Pharmaceutical Sciences

    6 publications · 661 citations

    6

    h-index

  3. Chemical and Pharmaceutical Bulletin

    5 publications · 86 citations

    5

    h-index

  4. Chemosphere

    3 publications · 163 citations

    3

    h-index

  5. Journal of the American Chemical Society

    JACS · 3 publications · 251 citations

    3

    h-index

1–5