Concepedia

Permeability-limited Distribution

Permeability-Limited Distribution is a pharmacokinetic distribution model in which the rate of drug transport into a tissue is primarily governed by the membrane permeability characteristics of the tissue's cellular barriers rather than by blood flow or passive diffusion gradients.

33

Publications

1.7K

Citations

179

Authors

74

Institutions

Publications per year

2017–2026

9

Parents

Publications

33

Capillary Exchange Modeling

Carl A. Goresky, Wilfred H. Ziegler, Glen G. Bach et al. · Circulation Research · 1970 · 183 citations · Full text

, , +15

Physiologically Based Pharmacokinetics of Cyclosporine A: Extension to Tissue Distribution Kinetics in Rats and Scale-up to Human

R. Kawai, Chiaki Tanaka, Malcolm Rowland · Journal of Pharmacology and Experimental Therapeutics · 1998 · 155 citations

, , +16

The Pentameric Vertex Proteins Are Necessary for the Icosahedral Carboxysome Shell to Function as a CO2 Leakage Barrier

Fei Cai, Balaraj B. Menon, Gordon C. Cannon et al. · PLoS ONE · 2009 · 133 citations · Full text

, , +13

Safe long-term repeated disruption of the blood-brain barrier using an implantable ultrasound device: a multiparametric study in a primate model

Catherine Horodyckid, Michael Canney, Alexandre Vignot et al. · Journal of neurosurgery · 2016 · 123 citations · Full text

, , +17

Passive Permeation of Organic Compounds through Biological Tissue: a Non-Steady-State Theory

John T. Penniston, Laurel Beckett, Donald L. Bentley et al. · Molecular Pharmacology · 1969 · 118 citations

, , +17

1–5 of 33

Authors

179

  1. AM
    Abraham M. Lenhoff

    University of Delaware, United States

    2 publications · 38 citations

    2

    h-index

  2. EN
    E. N. Lightfoot

    University of Wisconsin–Madison, United States

    2 publications · 38 citations

    2

    h-index

  3. JE
    Jim E. Riviere

    North Carolina State University, United States

    1 publications · 37 citations

    1

    h-index

  4. MT
    Md Tariqul Haque Tuhin

    University of the Pacific, United States

    1 publications · 12 citations

    1

    h-index

  5. HD
    Hadassa Degani

    Weizmann Institute of Science, Israel

    1 publications · 40 citations

    1

    h-index

1–5 of 179

Institutions

74

  1. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    3 publications

    273 citations

  2. University of Wisconsin–Madison

    Madison, United States

    2 h-index

    4 publications

    76 citations

  3. University of Wisconsin System

    Madison, United States

    2 h-index

    4 publications

    76 citations

  4. University of the Pacific

    Stockton, United States

    2 h-index

    15 publications

    174 citations

  5. CEA Paris-Saclay

    Gif-sur-Yvette, France

    2 h-index

    2 publications

    150 citations

  6. Oregon Health & Science University

    Portland, United States

    1 h-index

    3 publications

    126 citations

  7. The Barbara Ann Karmanos Cancer Institute

    Detroit, United States

    1 h-index

    1 publications

    10 citations

  8. Kunming Medical University

    Kunming, China

    1 h-index

    9 publications

    306 citations

1–8 of 74

Venues

  1. Journal of Pharmaceutical Sciences

    2 publications · 105 citations

    2

    h-index

  2. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 2 publications · 50 citations

    2

    h-index

  3. Journal of Theoretical Biology

    2 publications · 38 citations

    2

    h-index

  4. BMC Clinical Pharmacology

    1 publications · 23 citations

    1

    h-index

  5. Circulation Research

    1 publications · 183 citations

    1

    h-index

1–5