Concepedia

Peripheral Deletion

Peripheral Deletion is a mechanism of peripheral tolerance in which self-reactive T cells are induced to undergo apoptosis in peripheral tissues, thereby preventing autoimmunity through the elimination of potentially pathogenic lymphocytes outside the thymus.

124

Publications

11.6K

Citations

559

Authors

193

Institutions

Publications per year

2017–2026

4

Variants

Peripheral T-cell Deletion

Parents

Publications

124

Peripheral deletion of antigen-reactive T cells in oral tolerance

Youhai Chen, Jun-ichi Inobe, Reinhard Marks et al. · Nature · 1995 · 785 citations

, , +16

Excess BAFF Rescues Self-Reactive B Cells from Peripheral Deletion and Allows Them to Enter Forbidden Follicular and Marginal Zone Niches

Marilyn Thien, Tri Giang Phan, Sandra Gardam et al. · Immunity · 2004 · 724 citations · Full text

, , +16

Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

Christian Kurts, Hiroshi Kosaka, Jacques F.A.P. Miller et al. · The Journal of Experimental Medicine · 1997 · 700 citations · Full text

, , +17

Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover.

Lars E. French, Michael Hahne, I. Viard et al. · The Journal of Cell Biology · 1996 · 458 citations · Full text

, , +17

Human lung carcinomas express Fas ligand.

G A Niehans, Thomas Brunner, Sandra Frizelle et al. · PubMed · 1997 · 396 citations · Full text

, , +17

1–5 of 124

Authors

559

  1. WR
    William R. Heath

    Walter and Eliza Hall Institute of Medical Research, Australia

    6 publications · 1.4K citations

    6

    h-index

  2. MS
    Megan Sykes

    Massachusetts General Hospital, United States

    6 publications · 783 citations

    6

    h-index

  3. TW
    Thomas Wekerle

    Medical University of Vienna, Austria

    6 publications · 665 citations

    6

    h-index

  4. JF
    Jacques F.A.P. Miller

    Walter and Eliza Hall Institute of Medical Research, Australia

    5 publications · 1.4K citations

    5

    h-index

  5. IN
    Ian Nicholas Crispe

    University of Washington, United States

    5 publications · 417 citations

    5

    h-index

1–5 of 559

Institutions

193

  1. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    9 h-index

    33 publications

    7.7K citations

  2. Harvard University

    Cambridge, United States

    8 h-index

    32 publications

    7.1K citations

  3. Massachusetts General Hospital

    Boston, United States

    7 h-index

    33 publications

    4.9K citations

  4. National Institutes of Health

    Bethesda, United States

    6 h-index

    20 publications

    1K citations

  5. Ludwig Cancer Research

    Zurich, Switzerland

    6 h-index

    19 publications

    1.6K citations

  6. Yale University

    New Haven, United States

    6 h-index

    13 publications

    1.1K citations

  7. The University of Melbourne

    Melbourne, Australia

    5 h-index

    13 publications

    358 citations

  8. The Royal Melbourne Hospital

    Melbourne, Australia

    5 h-index

    23 publications

    6.8K citations

1–8 of 193

Venues

  1. The Journal of Immunology

    JI · 38 publications · 2.1K citations

    28

    h-index

  2. European Journal of Immunology

    EJI · 19 publications · 1.3K citations

    17

    h-index

  3. The Journal of Experimental Medicine

    10 publications · 2K citations

    10

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 1K citations

    9

    h-index

  5. PubMed

    Repository · 8 publications · 771 citations

    8

    h-index

1–5