Concepedia

Perfusion Rate Optimization

Perfusion Rate Optimization is a methodological framework in perfusion bioreactor research that systematically determines the optimal flow rate of culture medium to maximize cellular viability, function, and mass transfer efficiency while minimizing shear stress and nutrient gradients.

51

Publications

2K

Citations

218

Authors

75

Institutions

Publications per year

2017–2026

19

Parents

Publications

51

Optimizing the medium perfusion rate in bone tissue engineering bioreactors

Warren L. Grayson, Darja Marolt, Sarindr Bhumiratana et al. · Biotechnology and Bioengineering · 2010 · 149 citations

, , +17

Fermentor temperature as a tool for control of high-density perfusion cultures of mammalian cells

Sandra Chuppa, Yeong-Shou Tsai, Sungjin Yoon et al. · Biotechnology and Bioengineering · 1997 · 134 citations

, , +16

Optimizing capacity utilization by large scale 3000 L perfusion in seed train bioreactors

Michael Pohlscheidt, Melanie Jacobs, Stefan Wolf et al. · Biotechnology Progress · 2012 · 95 citations

, , +17

Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates

Jae‐Sung Park, Yawen Li, François Berthiaume et al. · Biotechnology and Bioengineering · 2007 · 89 citations

, , +17

Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor

Anniina J. Valkama, Hanna Leinonen, Eevi M. Lipponen et al. · Gene Therapy · 2017 · 88 citations · Full text

, , +17

1–5 of 51

Authors

218

  1. AC
    Andreas Castan

    KTH Royal Institute of Technology, Sweden

    3 publications · 90 citations

    3

    h-index

  2. HM
    Hikaru Matsuda

    The University of Osaka, Japan

    2 publications · 71 citations

    2

    h-index

  3. NV
    N. V. Connelly

    Union Institute & University, United States

    2 publications · 81 citations

    2

    h-index

  4. JM
    Jens Matuszczyk

    Sartorius (Germany), Germany

    2 publications · 86 citations

    2

    h-index

  5. VM
    V. M. Yabannavar

    Massachusetts Institute of Technology, United States

    2 publications · 81 citations

    2

    h-index

1–5 of 218

Institutions

75

  1. University of British Columbia

    Vancouver, Canada

    2 h-index

    7 publications

    397 citations

  2. Universidade Nova de Lisboa

    Lisbon, Portugal

    2 h-index

    1 publications

    27 citations

  3. The University of Osaka

    Osaka, Japan

    2 h-index

    14 publications

    448 citations

  4. Instituto de Biologia Experimental e Tecnológica

    Oeiras, Portugal

    2 h-index

    5 publications

    135 citations

  5. BOKU University

    Vienna, Austria

    2 h-index

    5 publications

    126 citations

  6. Merck Serono S.A. (Switzerland)

    Aubonne, Switzerland

    2 h-index

    6 publications

    188 citations

  7. Sartorius (Germany)

    Göttingen, Germany

    2 h-index

    7 publications

    311 citations

  8. Fukushima Medical University

    Fukushima, Japan

    2 h-index

    14 publications

    448 citations

1–8 of 75

Venues

  1. Biotechnology Progress

    9 publications · 440 citations

    9

    h-index

  2. Biotechnology and Bioengineering

    8 publications · 611 citations

    8

    h-index

  3. Cytotechnology

    5 publications · 158 citations

    5

    h-index

  4. Frontiers in Bioengineering and Biotechnology

    2 publications · 59 citations

    3

    h-index

  5. 3

    h-index

1–5