Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis

David Reinhart, Lukas Damjanovic, Christian Kaisermayer, +7

Biotechnology Journal

OocyteEngineeringImmunologyCell CultureEnzymatic Modification +19

Highly active engineered IgG3 antibodies against SARS-CoV-2

Somanath Kallolimath, Lin Sun, Roman Palt, +6

Proceedings of the National Academy of Sciences

Increased in vitro neutralizing activity of SARS-CoV-2 IgA1 dimers compared to monomers and IgG

Lin Sun, Somanath Kallolimath, Roman Palt, +5

Proceedings of the National Academy of Sciences

A human monocytic NF-κB fluorescent reporter cell line for detection of microbial contaminants in biological samples

Claire Battin, Annika Hennig, Patrick Mayrhofer, +4

PLoS ONE

EngineeringMicrobial PathogensPathogen DetectionInnate Immune SystemImmunology +28

Proteomic differences in recombinant CHO cells producing two similar antibody fragments

Wolfgang Sommeregger, Patrick Mayrhofer, Willibald Steinfellner, +5

Biotechnology and Bioengineering

Humoral ResponseImmunologyProteomic DifferencesAntigen ProcessingSimilar Antibody Fragments +18

Antibody humanization by molecular dynamics simulations—<i>in‐silico</i> guided selection of critical backmutations

Christian Margreitter, Patrick Mayrhofer, Renate Kunert, +1

Journal of Molecular Recognition

Shake tube perfusion cell cultures are suitable tools for the prediction of limiting substrate, <scp>CSPR</scp>, bleeding strategy, growth and productivity behavior

Patrick Mayrhofer, Andreas Castan, Renate Kunert

Journal of Chemical Technology & Biotechnology

Perfusion ApplicationsEngineeringBioreactor TechnologyPerfusion Scale‐down ModelsCell Culture +20

Rapid development of clone‐specific, high‐performing perfusion media from established feed supplements

Patrick Mayrhofer, David Reinhart, Andreas Castan, +1

Biotechnology Progress

Accurate comparison of antibody expression levels by reproducible transgene targeting in engineered recombination-competent CHO cells

Patrick Mayrhofer, Bernhard Kratzer, Wolfgang Sommeregger, +7

Applied Microbiology and Biotechnology

Comparative Antigenicity of Thiourea and Adipic Amide Linked Neoglycoconjugates Containing Modified Oligomannose Epitopes for the Carbohydrate-Specific anti-HIV Antibody 2G12

Nino Trattnig, Patrick Mayrhofer, Renate Kunert, +3

Bioconjugate Chemistry