Concepedia

Peptide Sequence Optimization

Peptide Sequence Optimization is a computational or experimental methodology that systematically modifies the amino acid sequence of a peptide to enhance its pharmacological properties, stability, or target specificity while maintaining structural integrity within the context of drug discovery.

325

Publications

15.8K

Citations

1.7K

Authors

568

Institutions

Publications per year

2017–2026

128

Parents

Publications

325

Determination of the Specific Substrate Sequence Motifs of Protein Kinase C Isozymes

Kiyotaka Nishikawa, Alex Toker, Franz‐Josef Johannes et al. · Journal of Biological Chemistry · 1997 · 562 citations · Full text

, , +17

iACP: a sequence-based tool for identifying anticancer peptides

Wei Chen, Hui Ding, Pengmian Feng et al. · Oncotarget · 2016 · 436 citations · Full text

, , +15

Automated amino acid sequence of small peptides utilizing Polybrene

David G. Klapper, Charles E. Wilde, J. Donald Capra · Analytical Biochemistry · 1978 · 321 citations

, , +9

Bioinformatics approaches, prospects and challenges of food bioactive peptide research

Chibuike C. Udenigwe · Trends in Food Science & Technology · 2014 · 293 citations

, , +14

Control of self-assembling oligopeptide matrix formation through systematic variation of amino acid sequence

Michael R. Caplan, Elissa M. Schwartzfarb, Shuguang Zhang et al. · Biomaterials · 2002 · 280 citations

, , +15

1–5 of 325

Authors

1.7K

  1. GS
    Gisbert Schneider

    ETH Zurich, Switzerland

    6 publications · 306 citations

    6

    h-index

  2. CK
    Carol K. Hall

    North Carolina State University, United States

    5 publications · 111 citations

    5

    h-index

  3. XX
    Xingqing Xiao

    North Carolina State University, United States

    5 publications · 111 citations

    5

    h-index

  4. CA
    Christodoulos A. Floudas

    Princeton University, United States

    4 publications · 203 citations

    4

    h-index

  5. EG
    Ernest Giralt

    Universitat de Barcelona, Spain

    4 publications · 92 citations

    4

    h-index

1–5 of 1.7K

Institutions

568

  1. The University of Tokyo

    Tokyo, Japan

    9 h-index

    30 publications

    1.1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    30 publications

    946 citations

  3. University of Electronic Science and Technology of China

    Chengdu, China

    6 h-index

    14 publications

    1.6K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    6 h-index

    31 publications

    2.9K citations

  5. Cornell University

    Ithaca, United States

    5 h-index

    18 publications

    680 citations

  6. Princeton University

    Princeton, United States

    5 h-index

    20 publications

    1.1K citations

  7. Freie Universität Berlin

    Berlin, Germany

    5 h-index

    21 publications

    928 citations

  8. ETH Zurich

    Zurich, Switzerland

    5 h-index

    31 publications

    1.6K citations

1–8 of 568

Venues

  1. Journal of Biological Chemistry

    JBC · 9 publications · 1.1K citations

    9

    h-index

  2. Journal of Medicinal Chemistry

    8 publications · 378 citations

    8

    h-index

  3. Journal of the American Chemical Society

    JACS · 8 publications · 588 citations

    8

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 7 publications · 310 citations

    7

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 634 citations

    7

    h-index

1–5