Peptide Linkers is a specialized type of biodegradable molecular spacer composed of amino acid sequences designed to covalently connect a therapeutic peptide to a modifying agent or carrier moiety, enabling controlled release or enhanced pharmacokinetic properties in the context of prodrug strategies.
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281
Novel Peptide Linkers for Highly Potent Antibody−Auristatin Conjugate
Svetlana O. Doronina, Tim D. Bovee, David W. Meyer et al. · Bioconjugate Chemistry · 2008 · 176 citations
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Centre National de la Recherche Scientifique
Paris, France
9 h-index
40 publications
1.1K citations
The University of Queensland
Brisbane, Australia
8 h-index
41 publications
1.3K citations
University of Cambridge
Cambridge, United Kingdom
6 h-index
47 publications
1.6K citations
Howard Hughes Medical Institute
Chevy Chase, United States
6 h-index
12 publications
654 citations
Massachusetts Institute of Technology
Cambridge, United States
5 h-index
26 publications
520 citations
University of California, Davis
Davis, United States
5 h-index
17 publications
622 citations
Seagen (United States)
Bothell, United States
5 h-index
37 publications
6K citations
Universitat de Barcelona
Barcelona, Spain
5 h-index
15 publications
301 citations
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- Bioconjugate Chemistry
20 publications · 1.2K citations
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- Organic Letters
OL · 10 publications · 212 citations
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- Tetrahedron Letters
9 publications · 297 citations
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- Organic & Biomolecular Chemistry
9 publications · 282 citations
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- Bioorganic & Medicinal Chemistry Letters
7 publications · 204 citations
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