Concepedia

Pattern Recognition Receptor Defects

Pattern Recognition Receptor Defects is a genetic or functional impairment in the innate immune system’s pattern recognition receptors that compromises the detection of pathogen-associated molecular patterns, thereby increasing susceptibility to infection.

22

Publications

1.1K

Citations

175

Authors

76

Institutions

Publications per year

2017–2026

4

Variants

Prr Defects

Parents

Publications

22

TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner

Andrea Ablasser, Inga Hemmerling, Jonathan L. Schmid‐Burgk et al. · The Journal of Immunology · 2014 · 253 citations · Full text

, , +17

In a novel form of IFN-γ receptor 1 deficiency, cell surface receptors fail to bind IFN-γ

Emmanuelle Jouanguy, Stéphanie Boisson‐Dupuis, Annaïck Pallier et al. · Journal of Clinical Investigation · 2000 · 154 citations · Full text

, , +14

Gut microbial DL-endopeptidase alleviates Crohn’s disease via the NOD2 pathway

Jie Gao, Xinmei Zhao, Shixian Hu et al. · Cell Host & Microbe · 2022 · 105 citations · Full text

, , +17

TLR9 Activation Induces Normal Neutrophil Responses in a Child with IRAK-4 Deficiency: Involvement of the Direct PI3K Pathway

C. Hoarau, Bénédicte Gérard, E. Lescanne et al. · The Journal of Immunology · 2007 · 68 citations · Full text

, , +17

Defective Reticuloendothelial System Fc-Receptor Function in Patients with Acquired Immunodeficiency Syndrome

Biggi Bender, Martin Frank, Thomas J. Lawley et al. · The Journal of Infectious Diseases · 1985 · 68 citations

, , +13

1–5 of 22

Authors

175

  1. JC
    Jean‐Laurent Casanova

    Inserm, France

    3 publications · 206 citations

    3

    h-index

  2. LA
    Leo A. B. Joosten

    Radboud University Nijmegen, Netherlands

    2 publications · 77 citations

    2

    h-index

  3. CP
    Capucine Pïcard

    Inserm, France

    2 publications · 52 citations

    2

    h-index

  4. AP
    Anne Puel

    Inserm, France

    2 publications · 52 citations

    2

    h-index

  5. OE
    Orly Elpeleg

    Hadassah Medical Center, Israel

    1 publications · 38 citations

    1

    h-index

1–5 of 175

Institutions

76

  1. Inserm

    Paris, France

    5 h-index

    33 publications

    2.3K citations

  2. Université Paris Cité

    Paris, France

    3 h-index

    22 publications

    890 citations

  3. Institut National de Santé Publique

    Tunis, Tunisia

    2 h-index

    10 publications

    524 citations

  4. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    9 publications

    490 citations

  5. Délégation Paris 5

    Paris, France

    2 h-index

    12 publications

    660 citations

  6. Human Genetic of Infectious Diseases

    Paris, France

    2 h-index

    11 publications

    1.1K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    2 h-index

    8 publications

    108 citations

  8. Hôpital Necker-Enfants Malades

    Paris, France

    2 h-index

    10 publications

    1.4K citations

1–8 of 76

Venues

  1. PubMed

    Repository · 3 publications · 72 citations

    3

    h-index

  2. The Journal of Immunology

    JI · 2 publications · 321 citations

    2

    h-index

  3. Journal of Endotoxin Research

    2 publications · 57 citations

    2

    h-index

  4. The Journal of Infectious Diseases

    JID · 1 publications · 68 citations

    1

    h-index

  5. Tissue Antigens

    1 publications · 17 citations

    1

    h-index

1–5