Concepedia

Pathway-based Pharmacogenomics

Pathway-Based Pharmacogenomics is a pharmacogenomic approach that integrates genetic variation data with biological pathway information to elucidate how coordinated molecular interactions influence individual responses to cancer therapies, particularly in the context of immunotherapy, by shifting focus from single-gene effects to functionally related gene networks.

14

Publications

792

Citations

140

Authors

50

Institutions

Publications per year

2017–2026

3

Parents

Publications

14

A Pharmacogenomic Landscape in Human Liver Cancers

Zhixin Qiu, Hong Li, Zhengtao Zhang et al. · Cancer Cell · 2019 · 218 citations · Full text

, , +14

Genetic Variations in Radiation and Chemotherapy Drug Action Pathways Predict Clinical Outcomes in Esophageal Cancer

Xifeng Wu, Jian Gu, Tsung‐Teh Wu et al. · Journal of Clinical Oncology · 2006 · 167 citations

, , +17

Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver

Kathrin Klein, Stefan Winter, Miia Turpeinen et al. · Frontiers in Pharmacology · 2010 · 97 citations · Full text

, , +13

Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy

Xifeng Wu, Charles Lu, Yuanqing Ye et al. · Pharmacogenetics and Genomics · 2008 · 49 citations · Full text

, , +17

A First Step toward Personalized Medicine in Osteosarcoma: Pharmacogenetics as Predictive Marker of Outcome after Chemotherapy-Based Treatment

Melanie M. Hagleitner, Marieke J. H. Coenen, Hans Gelderblom et al. · Clinical Cancer Research · 2015 · 45 citations

, , +17

1–5 of 14

Authors

140

  1. XW
    Xifeng Wu

    The University of Texas MD Anderson Cancer Center, United States

    3 publications · 250 citations

    3

    h-index

  2. JG
    Jian Gu

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 216 citations

    2

    h-index

  3. LW
    Liewei Wang

    Mayo Clinic, United States

    2 publications · 41 citations

    2

    h-index

  4. HY
    Hushan Yang

    Thomas Jefferson University, United States

    1 publications · 49 citations

    1

    h-index

  5. MS
    Matthias Schwab

    Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Germany

    1 publications · 97 citations

    1

    h-index

1–5 of 140

Institutions

50

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    3 h-index

    30 publications

    3K citations

  2. Mayo Clinic

    Rochester, United States

    2 h-index

    10 publications

    188 citations

  3. Tokyo Institute of Technology

    Tokyo, Japan

    1 h-index

    1 publications

    22 citations

  4. University of California, San Francisco

    San Francisco, United States

    1 h-index

    9 publications

    369 citations

  5. Second Military Medical University

    Shanghai, China

    1 h-index

    2 publications

    436 citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    1 h-index

    1 publications

    12 citations

  7. Shanghai Institutes for Biological Sciences

    Shanghai, China

    1 h-index

    6 publications

    1.3K citations

  8. National University of Singapore

    Singapore, Singapore

    1 h-index

    4 publications

    88 citations

1–8 of 50

Venues

  1. Frontiers in Pharmacology

    2 publications · 126 citations

    2

    h-index

  2. Journal of Human Genetics

    1 publications · 41 citations

    1

    h-index

  3. OMICS A Journal of Integrative Biology

    1 publications · 12 citations

    1

    h-index

  4. BMC Cancer

    1 publications · 22 citations

    1

    h-index

  5. Journal of Clinical Oncology

    1 publications · 167 citations

    1

    h-index

1–5