Concepedia

Pathway Yield Optimization

Pathway Yield Optimization is a computational or mathematical framework within metabolic engineering that systematically enhances the stoichiometric or flux-based output of a target biochemical product in a designed pathway by adjusting enzymatic activities, reaction steps, or regulatory constraints to maximize conversion efficiency from substrates to products.

7

Publications

813

Citations

30

Authors

22

Institutions

Publications per year

2017–2026

1

Parents

Publications

7

Improving fatty acids production by engineering dynamic pathway regulation and metabolic control

Peng Xu, Lingyun Li, Fuming Zhang et al. · Proceedings of the National Academy of Sciences · 2014 · 496 citations · Full text

, , +17

Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield

Yongkun Lv, Yang Gu, Jingliang Xu et al. · Metabolic Engineering · 2020 · 126 citations · Full text

, , +16

Coping with complexity: Machine learning optimization of cell‐free protein synthesis

Filippo Caschera, Mark A. Bedau, Andrew Buchanan et al. · Biotechnology and Bioengineering · 2011 · 78 citations

, , +12

Optimization of biotechnological systems through geometric programming

Alberto Marı́n-Sanguino, Eberhard O. Voit, Carlos González‐Alcón et al. · Theoretical Biology and Medical Modelling · 2007 · 44 citations · Full text

, , +17

Tailoring strain construction strategies for muconic acid production in S. cerevisiae and E. coli

Nils J. H. Averesch, Jens O. Krömer · Metabolic Engineering Communications · 2014 · 38 citations · Full text

, , +17

1–5 of 7

Authors

30

  1. PX
    Peng Xu

    University of Maryland, Baltimore County, United States

    2 publications · 622 citations

    2

    h-index

  2. EO
    Eberhard O. Voit

    Georgia Institute of Technology, United States

    2 publications · 59 citations

    2

    h-index

  3. MS
    Mario Signore

    Medical University of South Carolina, United States

    1 publications · 15 citations

    1

    h-index

  4. GS
    Gregory Stephanopoulos

    Massachusetts Institute of Technology, United States

    1 publications · 496 citations

    1

    h-index

  5. NV
    Néstor V. Torres

    Universidad de La Laguna, Spain

    1 publications · 44 citations

    1

    h-index

1–5 of 30

Institutions

22

  1. University of Florence

    Florence, Italy

    1 h-index

    1 publications

    16 citations

  2. Medical University of South Carolina

    Charleston, United States

    1 h-index

    2 publications

    30 citations

  3. Zhengzhou University

    Zhengzhou, China

    1 h-index

    2 publications

    252 citations

  4. Jiangnan University

    Wuxi, China

    1 h-index

    3 publications

    378 citations

  5. Prothena (United States)

    South San Francisco, United States

    1 h-index

    1 publications

    78 citations

  6. Johns Hopkins University

    Baltimore, United States

    1 h-index

    1 publications

    16 citations

  7. Rensselaer Polytechnic Institute

    Troy, United States

    1 h-index

    4 publications

    2K citations

  8. University of Catania

    Catania, Italy

    1 h-index

    1 publications

    16 citations

1–8 of 22

Venues

  1. Biotechnology and Bioengineering

    2 publications · 93 citations

    2

    h-index

  2. Theoretical Biology and Medical Modelling

    1 publications · 44 citations

    1

    h-index

  3. Metabolic Engineering

    1 publications · 126 citations

    1

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 496 citations

    1

    h-index

  5. Metabolic Engineering Communications

    1 publications · 38 citations

    1

    h-index

1–5