Concepedia

Par-protein Complex

A Par-Protein Complex is a conserved protein complex that establishes and maintains cell polarity during gastrulation by spatially organizing downstream effectors through asymmetric localization of Par proteins at specific cortical domains.

91

Publications

8.1K

Citations

474

Authors

186

Institutions

Publications per year

2017–2026

17

Variants

Par Complex

Parents

Publications

91

Functional interaction between PARP‐1 and PARP‐2 in chromosome stability and embryonic development in mouse

Josiane Ménissier de Murcia, Michelle Ricoul, Laurence Tartier et al. · The EMBO Journal · 2003 · 630 citations · Full text

, , +13

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

Joerg Betschinger, Karl Mechtler, Juergen A. Knoblich · Nature · 2003 · 568 citations

, , +14

Drosophila PAR-1 and 14-3-3 Inhibit Bazooka/PAR-3 to Establish Complementary Cortical Domains in Polarized Cells

Richard Benton, Daniel St Johnston · Cell · 2003 · 410 citations · Full text

, , +15

Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization

Frederik Wirtz‐Peitz, Takashi Nishimura, Juergen A. Knoblich · Cell · 2008 · 368 citations · Full text

, , +17

PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain

Jennine M. Dawicki-McKenna, Marie-France Langelier, Jamie E. DeNizio et al. · Molecular Cell · 2015 · 353 citations · Full text

, , +8

1–5 of 91

Authors

474

  1. JA
    Juergen A. Knoblich

    Institute of Molecular Biotechnology, Austria

    4 publications · 1.2K citations

    4

    h-index

  2. SO
    Shigeo Ohno

    Yokohama City University, Japan

    4 publications · 660 citations

    4

    h-index

  3. TW
    Takashi Watanabe

    Nagoya University, Japan

    3 publications · 182 citations

    3

    h-index

  4. KK
    Kozo Kaibuchi

    Nagoya University, Japan

    3 publications · 182 citations

    3

    h-index

  5. MK
    Motoyuki Kohjima

    Kyushu University, Japan

    2 publications · 122 citations

    2

    h-index

1–5 of 474

Institutions

186

  1. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    6 publications

    975 citations

  2. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    5 publications

    720 citations

  3. Japan Science and Technology Agency

    Tokyo, Japan

    4 h-index

    4 publications

    281 citations

  4. Yokohama City University

    Yokohama, Japan

    4 h-index

    4 publications

    660 citations

  5. The Gurdon Institute

    Cambridge, United Kingdom

    3 h-index

    3 publications

    618 citations

  6. National Institutes of Health

    Bethesda, United States

    3 h-index

    3 publications

    244 citations

  7. University of Washington

    Seattle, United States

    3 h-index

    3 publications

    156 citations

  8. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    3 publications

    493 citations

1–8 of 186

Venues

  1. Developmental Biology

    8 publications · 563 citations

    8

    h-index

  2. Journal of Biological Chemistry

    JBC · 7 publications · 470 citations

    7

    h-index

  3. Current Biology

    6 publications · 1K citations

    6

    h-index

  4. Development

    5 publications · 351 citations

    5

    h-index

  5. Developmental Cell

    4 publications · 427 citations

    4

    h-index

1–5