Concepedia

Pain Hypersensitivity

Pain Hypersensitivity is a pathophysiological condition characterized by an amplified nociceptive response to sensory stimuli due to heightened neuronal excitability within the central nervous system, distinguishing it from peripheral sensitization by its origin in central neuroplastic changes rather than peripheral tissue damage.

1.7K

Publications

127.6K

Citations

7.4K

Authors

1.7K

Institutions

Publications per year

2017–2026

502

Parents

Publications

1.7K

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

Michael J. Caterina, Andreas Leffler, Annika B. Malmberg et al. · Science · 2000 · 3.5K citations

, , +17

Evidence for a central component of post-injury pain hypersensitivity

Clifford J. Woolf · Nature · 1983 · 2.1K citations

, , +14

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

Clifford J. Woolf · Pain · 1991 · 2K citations

, , +17

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

Robert E. Sorge, Josiane C.S. Mapplebeck, Sarah F. Rosen et al. · Nature Neuroscience · 2015 · 1.4K citations · Full text

, , +15

Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

Tarek A. Samad, Kimberly A. Moore, Adam Sapirstein et al. · Nature · 2001 · 1.3K citations

, , +14

1–5 of 1.7K

Authors

7.4K

  1. CJ
    Clifford J. Woolf

    Harvard University, United States

    34 publications · 11.8K citations

    32

    h-index

  2. LA
    Lars Arendt‐Nielsen

    Aalborg University, Denmark

    45 publications · 3.2K citations

    29

    h-index

  3. CF
    César Fernández‐de‐las‐Peñas

    Universidad Rey Juan Carlos, Spain

    30 publications · 2.1K citations

    22

    h-index

  4. JS
    Jeffrey S. Mogil

    McGill University, Canada

    23 publications · 4K citations

    21

    h-index

  5. RT
    Rolf‐Detlef Treede

    Heidelberg University, Germany

    22 publications · 2.3K citations

    20

    h-index

1–5 of 7.4K

Institutions

1.7K

  1. Harvard University

    Cambridge, United States

    41 h-index

    220 publications

    41.4K citations

  2. University College London

    London, United Kingdom

    36 h-index

    112 publications

    23.6K citations

  3. Aalborg University

    Aalborg, Denmark

    32 h-index

    124 publications

    7.6K citations

  4. McGill University

    Montreal, Canada

    31 h-index

    240 publications

    37.8K citations

  5. Massachusetts General Hospital

    Boston, United States

    30 h-index

    133 publications

    32.9K citations

  6. Heidelberg University

    Heidelberg, Germany

    28 h-index

    173 publications

    11.4K citations

  7. Air Force Medical University

    Xi'an, China

    26 h-index

    201 publications

    9.1K citations

  8. King's College London

    London, United Kingdom

    25 h-index

    87 publications

    12K citations

1–8 of 1.7K

Venues

  1. Pain

    230 publications · 23.3K citations

    82

    h-index

  2. Journal of Neuroscience

    75 publications · 12.3K citations

    56

    h-index

  3. Molecular Pain

    67 publications · 3.4K citations

    38

    h-index

  4. Journal of Pain

    46 publications · 3K citations

    29

    h-index

  5. Brain Research

    36 publications · 2.8K citations

    27

    h-index

1–5