Concepedia

P-tefb Regulation

P-TEFb Regulation is a molecular mechanism within the transcriptional pausing pathway that specifically governs the activity of the Positive Transcription Elongation Factor b (P-TEFb) to control the transition of RNA polymerase II from promoter-proximal pausing into productive elongation.

302

Publications

31.7K

Citations

1.4K

Authors

405

Institutions

Publications per year

2017–2026

54

Variants

Positive Transcription Elongation Factor B Regulation

Parents

Publications

302

The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription

Moon Kyoo Jang, Kazuki Mochizuki, Meisheng Zhou et al. · Molecular Cell · 2005 · 1.3K citations · Full text

, , +14

Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4

Zhiyuan Yang, Jasper H. N. Yik, Ruichuan Chen et al. · Molecular Cell · 2005 · 1.1K citations · Full text

, , +10

Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

Yuerong Zhu, Tsafrira Peery, Junmin Peng et al. · Genes & Development · 1997 · 694 citations · Full text

, , +17

Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase

Nick F. Marshall, Junmin Peng, Xie Zhi et al. · Journal of Biological Chemistry · 1996 · 645 citations · Full text

, , +17

Flavopiridol Inactivates P-TEFb and Blocks Most RNA Polymerase II Transcription in Vivo

Sheng‐Hao Chao, David H. Price · Journal of Biological Chemistry · 2001 · 638 citations · Full text

, , +14

1–5 of 302

Authors

1.4K

  1. DH
    David H. Price

    University of Iowa, United States

    29 publications · 7K citations

    28

    h-index

  2. BM
    B. Matija Peterlin

    University of California, San Francisco, United States

    27 publications · 3.2K citations

    23

    h-index

  3. QZ
    Qiang Zhou

    University of California, Berkeley, United States

    24 publications · 3.8K citations

    21

    h-index

  4. MB
    Matjaž Barborič

    University of California, San Francisco, United States

    13 publications · 1.7K citations

    13

    h-index

  5. KF
    Koh Fujinaga

    University of California, San Francisco, United States

    13 publications · 1.4K citations

    13

    h-index

1–5 of 1.4K

Institutions

405

  1. University of California, San Francisco

    San Francisco, United States

    33 h-index

    140 publications

    15.8K citations

  2. University of Iowa

    Iowa City, United States

    26 h-index

    102 publications

    31.9K citations

  3. University of California, Berkeley

    Berkeley, United States

    21 h-index

    102 publications

    17.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    20 h-index

    110 publications

    8.6K citations

  5. National Institutes of Health

    Bethesda, United States

    17 h-index

    66 publications

    15.6K citations

  6. Xiamen University

    Xiamen, China

    17 h-index

    101 publications

    7.3K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    37 publications

    4.9K citations

  8. University of Oxford

    Oxford, United Kingdom

    11 h-index

    34 publications

    3K citations

1–8 of 405

Venues

  1. Journal of Biological Chemistry

    JBC · 41 publications · 6.2K citations

    35

    h-index

  2. Molecular and Cellular Biology

    MCB · 27 publications · 2.7K citations

    25

    h-index

  3. Nucleic Acids Research

    25 publications · 2K citations

    23

    h-index

  4. Genes & Development

    18 publications · 4.4K citations

    18

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 1.9K citations

    18

    h-index

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