Concepedia

Osteoblastic Niche

The Osteoblastic Niche is a specialized microenvironment within the bone marrow, characterized by its proximity to osteoblasts and its regulatory role in maintaining hematopoietic stem cell quiescence and self-renewal through direct cellular interactions and secreted signaling molecules.

196

Publications

16.7K

Citations

1.2K

Authors

397

Institutions

Publications per year

2017–2026

31

Variants

Osteoblast Niche

Parents

Publications

196

Osteoblastic cells regulate the haematopoietic stem cell niche

Laura M. Calvi, G. B. Adams, Kathryn Weibrecht et al. · Nature · 2003 · 3.4K citations

, , +13

Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche

Hiroki Yoshihara, Fumio Arai, Kentaro Hosokawa et al. · Cell stem cell · 2007 · 793 citations · Full text

, , +11

Mesenchymal Stem Cell Transplantation Reverses Multiorgan Dysfunction in Systemic Lupus Erythematosus Mice and Humans

Lingyun Sun, Kentaro Akiyama, Huayong Zhang et al. · Stem Cells · 2009 · 589 citations · Full text

, , +16

Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche

Michelle A. Lawson, Michelle M. McDonald, Nataša Kovačić et al. · Nature Communications · 2015 · 393 citations · Full text

, , +17

In vivo near-infrared fluorescence imaging of osteoblastic activity

Atif Zaheer, Robert E. Lenkinski, Ashfaq Mahmood et al. · Nature Biotechnology · 2001 · 382 citations

, , +14

1–5 of 196

Authors

1.2K

  1. LM
    Laura M. Calvi

    University of Rochester, United States

    5 publications · 3.8K citations

    5

    h-index

  2. TJ
    Ted J. Hofmann

    Children's Hospital of Philadelphia, United States

    4 publications · 423 citations

    4

    h-index

  3. TS
    Toshio Suda

    Keio University, Japan

    4 publications · 871 citations

    4

    h-index

  4. EM
    Edwin M. Horwitz

    St. Jude Children's Research Hospital, United States

    4 publications · 423 citations

    4

    h-index

  5. DT
    David T. Scadden

    Massachusetts General Hospital, United States

    4 publications · 3.7K citations

    4

    h-index

1–5 of 1.2K

Institutions

397

  1. Harvard University

    Cambridge, United States

    9 h-index

    50 publications

    37.5K citations

  2. University of Michigan

    Ann Arbor, United States

    6 h-index

    27 publications

    2.5K citations

  3. University of Pennsylvania

    Philadelphia, United States

    6 h-index

    16 publications

    1.6K citations

  4. University of Modena and Reggio Emilia

    Modena, Italy

    6 h-index

    28 publications

    2.7K citations

  5. Keio University

    Tokyo, Japan

    5 h-index

    29 publications

    9.1K citations

  6. University of Rochester

    Rochester, United States

    5 h-index

    17 publications

    11.4K citations

  7. University of Sheffield

    Sheffield, United Kingdom

    5 h-index

    27 publications

    2.6K citations

  8. Massachusetts General Hospital

    Boston, United States

    5 h-index

    21 publications

    35.6K citations

1–8 of 397

Venues

  1. Bone

    18 publications · 1K citations

    17

    h-index

  2. PLoS ONE

    10 publications · 444 citations

    10

    h-index

  3. Blood

    10 publications · 919 citations

    10

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 8 publications · 531 citations

    8

    h-index

  5. PubMed

    Repository · 8 publications · 267 citations

    8

    h-index

1–5