Concepedia

Oral Absorption Variability

Oral Absorption Variability is a pharmacokinetic construct that quantifies the degree of fluctuation in the fraction or rate of a drug absorbed into systemic circulation following oral administration, distinguishing it from other sources of pharmacokinetic variability by specifically reflecting inter- and intra-subject differences in gastrointestinal absorption processes.

33

Publications

1.6K

Citations

182

Authors

77

Institutions

Publications per year

2017–2026

6

Parents

Publications

33

Interpatient variability in bioavailability is related to the extent of absorption: Implications for bioavailability and bioequivalence studies

Edward T. Hellriegel, Thorir D. Bjornsson, Walter W. Hauck · Clinical Pharmacology & Therapeutics · 1996 · 180 citations

, , +15

A biopharmaceutical classification-based Right-First-Time formulation approach to reduce human pharmacokinetic variability and project cycle time from First-In-Human to clinical Proof-Of-Concept

M. Sherry Ku, Wendy Dulin · Pharmaceutical Development and Technology · 2010 · 172 citations

, , +17

Absorption, Distribution, Metabolism, and Excretion of Ximelagatran, an Oral Direct Thrombin Inhibitor, in Rats, Dogs, and Humans

Ulf G. Eriksson, Ulf Bredberg, Kurt‐Jürgen Hoffmann et al. · Drug Metabolism and Disposition · 2003 · 155 citations

, , +16

Variability in the Pharmacokinetics and Pharmacodynamics of Low Dose Aspirin in Healthy Male Volunteers

Irma H. Benedek, Amita Joshi, Henry J. Pieniaszek et al. · The Journal of Clinical Pharmacology · 1995 · 141 citations

, , +14

Oral absorption of the HIV protease inhibitors: a current update

Gregory C. Williams, Patrick J. Sinko · Advanced Drug Delivery Reviews · 1999 · 135 citations

, , +16

1–5 of 33

Authors

182

  1. SY
    Shinji Yamashita

    Setsunan University, Japan

    2 publications · 88 citations

    2

    h-index

  2. FA
    Fang

    1 publications · 46 citations

    1

    h-index

  3. RW
    R.A. Woutersen

    Access to Nutrition Foundation, Netherlands

    1 publications · 27 citations

    1

    h-index

  4. VT
    Valentina Tirelli

    Istituto Superiore di Sanità, Italy

    1 publications · 31 citations

    1

    h-index

  5. SR
    Saeed Rezaee

    Tehran University of Medical Sciences, Iran

    1 publications · 13 citations

    1

    h-index

1–5 of 182

Institutions

77

  1. Simcyp (United Kingdom)

    Sheffield, United Kingdom

    2 h-index

    5 publications

    92 citations

  2. Setsunan University

    Osaka, Japan

    2 h-index

    4 publications

    176 citations

  3. University at Buffalo, State University of New York

    Buffalo, United States

    2 h-index

    7 publications

    117 citations

  4. AstraZeneca (Sweden)

    Södertälje, Sweden

    1 h-index

    1 publications

    155 citations

  5. Wilmington University

    New Castle, United States

    1 h-index

    5 publications

    705 citations

  6. Tehran University of Medical Sciences

    Tehran, Iran

    1 h-index

    4 publications

    52 citations

  7. National Jewish Health

    Denver, United States

    1 h-index

    4 publications

    48 citations

  8. St Vincent's Hospital Melbourne

    Melbourne, Australia

    1 h-index

    4 publications

    212 citations

1–8 of 77

Venues

  1. Molecular Pharmaceutics

    3 publications · 111 citations

    3

    h-index

  2. Drug Metabolism and Disposition

    2 publications · 175 citations

    2

    h-index

  3. Antimicrobial Agents and Chemotherapy

    AAC · 2 publications · 61 citations

    2

    h-index

  4. American Journal of Health-System Pharmacy

    AJHP · 1 publications · 22 citations

    1

    h-index

  5. Pharmaceutical Development and Technology

    1 publications · 172 citations

    1

    h-index

1–5