Concepedia

Optimal Study Design

Optimal Study Design is a systematic framework within population pharmacokinetic-pharmacodynamic modeling that specifies the most efficient and informative combination of sampling times, sample sizes, dosing regimens, and measurement precision to maximize the accuracy and precision of parameter estimation while minimizing resource use and ethical concerns.

369

Publications

17.3K

Citations

1.2K

Authors

606

Institutions

Publications per year

2017–2026

64

Parents

Publications

369

Statistical power and optimal design in experiments in which samples of participants respond to samples of stimuli.

Jacob Westfall, David A. Kenny, Charles M. Judd · Journal of Experimental Psychology General · 2014 · 937 citations

, , +17

Optimally splitting cases for training and testing high dimensional classifiers

Kevin K. Dobbin, Richard Simon · BMC Medical Genomics · 2011 · 416 citations · Full text

, , +17

Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study

Alì Taher, Khaled M. Musallam, Mehran Karimi et al. · Blood · 2009 · 380 citations

, , +11

A Comparative Study of Techniques for Differential Expression Analysis on RNA-Seq Data

Zong Hong Zhang, Dhanisha J. Jhaveri, Vikki M. Marshall et al. · PLoS ONE · 2014 · 356 citations · Full text

, , +14

A clinician's guide for conducting randomized trials in individual patients.

Gordon Guyatt, David L. Sackett, Jonathan D. Adachi et al. · PubMed · 1988 · 276 citations

, , +16

1–5 of 369

Authors

1.2K

  1. LA
    Leon Aarons

    University of Manchester, United Kingdom

    14 publications · 365 citations

    13

    h-index

  2. KO
    Kayode Ogungbenro

    University of Manchester, United Kingdom

    14 publications · 444 citations

    13

    h-index

  3. SB
    Stephen B. Duffull

    University of Otago, New Zealand

    13 publications · 377 citations

    12

    h-index

  4. AC
    Andrew C. Hooker

    Uppsala University, Sweden

    10 publications · 303 citations

    10

    h-index

  5. HD
    Holger Dette

    Ruhr University Bochum, Germany

    10 publications · 464 citations

    10

    h-index

1–5 of 1.2K

Institutions

606

  1. University of Manchester

    Manchester, United Kingdom

    16 h-index

    52 publications

    2.4K citations

  2. Inserm

    Paris, France

    14 h-index

    27 publications

    1.2K citations

  3. Novartis (Switzerland)

    Basel, Switzerland

    12 h-index

    25 publications

    1.2K citations

  4. University of California, Los Angeles

    Los Angeles, United States

    10 h-index

    11 publications

    421 citations

  5. Uppsala University

    Uppsala, Sweden

    9 h-index

    24 publications

    664 citations

  6. University of Oxford

    Oxford, United Kingdom

    9 h-index

    19 publications

    1K citations

  7. MRC Biostatistics Unit

    Cambridge, United Kingdom

    9 h-index

    19 publications

    797 citations

  8. University of Otago

    Dunedin, New Zealand

    9 h-index

    12 publications

    284 citations

1–8 of 606

Venues

  1. Statistics in Medicine

    51 publications · 2.3K citations

    30

    h-index

  2. Biometrics

    15 publications · 663 citations

    14

    h-index

  3. Journal of Pharmacokinetics and Pharmacodynamics

    15 publications · 382 citations

    13

    h-index

  4. Journal of Biopharmaceutical Statistics

    JBS · 14 publications · 308 citations

    12

    h-index

  5. PubMed

    Repository · 10 publications · 1.2K citations

    10

    h-index

1–5