Concepedia

Nucleotide Selection Fidelity

Nucleotide Selection Fidelity is a biochemical accuracy metric that quantifies the ability of DNA polymerase to correctly select and incorporate the proper deoxyribonucleoside triphosphate complementary to the template strand during DNA synthesis, thereby distinguishing it from other kinetic or structural aspects of polymerase function.

18

Publications

1.2K

Citations

70

Authors

33

Institutions

Publications per year

2017–2026

2

Parents

Publications

18

On the fidelity of DNA replication: manganese mutagenesis in vitro

Robert A. Beckman, Albert S. Mildvan, Lawrence A. Loeb · Biochemistry · 1985 · 213 citations

, , +17

Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis

Alexandra Vaisman, Hong Ling, Roger Woodgate et al. · The EMBO Journal · 2005 · 182 citations · Full text

, , +7

Efficiency of Correct Nucleotide Insertion Governs DNA Polymerase Fidelity

William A. Beard, David D. Shock, Brian J. Vande Berg et al. · Journal of Biological Chemistry · 2002 · 133 citations · Full text

, , +15

Control of mutation frequency by bacteriophage T4 DNA polymerase. II. Accuracy of nucleotide selection by the L88 mutator, CB120 antimutator, and wild type phage T4 DNA polymerases.

Frances D. Gillin, Nancy G. Nossal · Journal of Biological Chemistry · 1976 · 82 citations · Full text

, , +15

Ribonucleotide Discrimination and Reverse Transcription by the Human Mitochondrial DNA Polymerase

Rajesh Kasiviswanathan, William C. Copeland · Journal of Biological Chemistry · 2011 · 75 citations · Full text

, , +15

1–5 of 18

Authors

70

  1. JY
    Jin Yu

    Beijing Computational Science Research Center, China

    2 publications · 37 citations

    2

    h-index

  2. LA
    Lawrence A. Loeb

    University of Washington, United States

    2 publications · 287 citations

    2

    h-index

  3. AB
    A. Blank

    University of Washington, United States

    1 publications · 74 citations

    1

    h-index

  4. RD
    Ralph Davis

    Stanford University, United States

    1 publications · 74 citations

    1

    h-index

  5. ZS
    Zucai Suo

    The Ohio State University, United States

    1 publications · 36 citations

    1

    h-index

1–5 of 70

Institutions

33

  1. National Institutes of Health

    Bethesda, United States

    4 h-index

    11 publications

    1.5K citations

  2. Beijing Computational Science Research Center

    Beijing, China

    3 h-index

    5 publications

    99 citations

  3. University of Colorado Boulder

    Boulder, United States

    2 h-index

    5 publications

    254 citations

  4. National Institute of Environmental Health Sciences

    Durham, United States

    2 h-index

    6 publications

    682 citations

  5. Molecular Sciences Institute

    Berkeley, United States

    1 h-index

    1 publications

    65 citations

  6. Applied Mathematics (United States)

    Gales Ferry, United States

    1 h-index

    2 publications

    52 citations

  7. Lawrence Berkeley National Laboratory

    Berkeley, United States

    1 h-index

    1 publications

    74 citations

  8. Florida State University

    Tallahassee, United States

    1 h-index

    1 publications

    26 citations

1–8 of 33

Venues

  1. Journal of Biological Chemistry

    JBC · 5 publications · 390 citations

    5

    h-index

  2. Biochemistry

    4 publications · 314 citations

    4

    h-index

  3. Nucleic Acids Research

    2 publications · 81 citations

    2

    h-index

  4. The EMBO Journal

    1 publications · 182 citations

    1

    h-index

  5. Cell Reports

    1 publications · 46 citations

    1

    h-index

1–5