Concepedia

Nonspecific Binding Reduction

Nonspecific Binding Reduction is a methodological strategy in surface immobilization that minimizes non-target interactions between biomolecules and solid supports by selectively passivating reactive sites or modifying surface chemistry to enhance binding specificity.

224

Publications

12.3K

Citations

1K

Authors

282

Institutions

Publications per year

2017–2026

29

Parents

Publications

224

Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes.

Kenneth S. Korach, Pamela J. Sarver, Kun Chae et al. · Molecular Pharmacology · 1988 · 432 citations

, , +17

Surface Acetylation of Polyamidoamine (PAMAM) Dendrimers Decreases Cytotoxicity while Maintaining Membrane Permeability

Rohit Kolhatkar, Kelly M. Kitchens, Peter W. Swaan et al. · Bioconjugate Chemistry · 2007 · 287 citations

, , +17

Differences among techniques for high‐abundant protein depletion

Nina Zolotarjova, James Martosella, Gordon R. Nicol et al. · PROTEOMICS · 2005 · 283 citations

, , +17

A Hydrophilic Azacyclooctyne for Cu-Free Click Chemistry

Ellen M. Sletten, Carolyn R. Bertozzi · Organic Letters · 2008 · 283 citations · Full text

, , +14

Surface Modification To Reduce Nonspecific Binding of Quantum Dots in Live Cell Assays

Elizabeth L. Bentzen, Ian D. Tomlinson, John N. Mason et al. · Bioconjugate Chemistry · 2005 · 273 citations

, , +17

1–5 of 224

Authors

1K

  1. TE
    Tag E. Mansour

    Stanford University, United States

    10 publications · 597 citations

    10

    h-index

  2. AT
    Akito Tanaka

    Hyogo Medical University, Japan

    3 publications · 111 citations

    3

    h-index

  3. SZ
    Shenfei Zong

    Southeast University, China

    2 publications · 60 citations

    2

    h-index

  4. ZW
    Zhuyuan Wang

    Southeast University, China

    2 publications · 60 citations

    2

    h-index

  5. HP
    Hana Popelková

    University of Michigan, United States

    2 publications · 72 citations

    2

    h-index

1–5 of 1K

Institutions

282

  1. Stanford University

    Stanford, United States

    10 h-index

    21 publications

    1.2K citations

  2. University of Washington

    Seattle, United States

    4 h-index

    17 publications

    253 citations

  3. Harvard University

    Cambridge, United States

    4 h-index

    10 publications

    1.6K citations

  4. United States Naval Research Laboratory

    Washington, United States

    4 h-index

    14 publications

    1K citations

  5. Johns Hopkins University

    Baltimore, United States

    3 h-index

    9 publications

    468 citations

  6. Roche (Switzerland)

    Basel, Switzerland

    3 h-index

    11 publications

    207 citations

  7. Texas A&M University

    College Station, United States

    3 h-index

    7 publications

    232 citations

  8. Nankai University

    Tianjin, China

    3 h-index

    14 publications

    470 citations

1–8 of 282

Venues

  1. PubMed

    Repository · 15 publications · 494 citations

    14

    h-index

  2. Analytical Chemistry

    14 publications · 809 citations

    14

    h-index

  3. Langmuir

    12 publications · 768 citations

    12

    h-index

  4. Journal of Biological Chemistry

    JBC · 12 publications · 932 citations

    11

    h-index

  5. ACS Applied Materials & Interfaces

    8 publications · 281 citations

    8

    h-index

1–5