Concepedia

Nonlinear Oral Bioavailability

Nonlinear Oral Bioavailability is a pharmacokinetic phenomenon in which the fraction of an orally administered drug that reaches systemic circulation varies disproportionately with dose due to capacity-limited processes in absorption, metabolism, or transport.

11

Publications

342

Citations

71

Authors

27

Institutions

Publications per year

2017–2026

2

Parents

Publications

11

Nonlinear assessment of phenytoin bioavailability

William J. Jusko, Jeffrey R. Koup, Gunnar Alván · Journal of Pharmacokinetics and Biopharmaceutics · 1976 · 93 citations

, , +14

Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children

Sophida Boonsathorn, Iek Cheng, Frank Kloprogge et al. · Clinical Pharmacokinetics · 2018 · 54 citations · Full text

, , +17

Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments

Joseph P. O’Shea, Waleed Faisal, Therese Ruane-O’Hora et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2015 · 33 citations

, , +16

To Apply Microdosing or Not? Recommendations to Single Out Compounds with Non-Linear Pharmacokinetics

Sieto Bosgra, Maria L.H. Vlaming, Wouter H. J. Vaes · Clinical Pharmacokinetics · 2015 · 33 citations

, , +11

Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability

Dennis Schade, Jürke Kotthaus, Lukas Riebling et al. · Journal of Pharmaceutical Sciences · 2015 · 28 citations

, , +15

1–5 of 11

Authors

71

  1. MB
    Michael B. Bottorff

    University of Tennessee Health Science Center, United States

    1 publications · 20 citations

    1

    h-index

  2. IS
    Isabel Spriet

    KU Leuven, Belgium

    1 publications · 17 citations

    1

    h-index

  3. JB
    John Booth

    University College London, United Kingdom

    1 publications · 54 citations

    1

    h-index

  4. ED
    Erwin Dreesen

    KU Leuven, Belgium

    1 publications · 17 citations

    1

    h-index

  5. KA
    Karel Allegaert

    KU Leuven, Belgium

    1 publications · 17 citations

    1

    h-index

1–5 of 71

Institutions

27

  1. St George's, University of London

    London, United Kingdom

    1 h-index

    1 publications

    54 citations

  2. Kyoto Pharmaceutical University

    Kyoto, Japan

    1 h-index

    5 publications

    65 citations

  3. University of Tennessee Health Science Center

    Memphis, United States

    1 h-index

    5 publications

    100 citations

  4. University at Buffalo, State University of New York

    Buffalo, United States

    1 h-index

    2 publications

    186 citations

  5. University College London

    London, United Kingdom

    1 h-index

    10 publications

    540 citations

  6. University of British Columbia

    Vancouver, Canada

    1 h-index

    4 publications

    40 citations

  7. Institutul Clinic Fundeni

    Bucharest, Romania

    1 h-index

    1 publications

    17 citations

  8. Mahidol University

    Bangkok, Thailand

    1 h-index

    1 publications

    54 citations

1–8 of 27

Venues

  1. Journal of Pharmaceutical Sciences

    4 publications · 72 citations

    4

    h-index

  2. Clinical Pharmacokinetics

    2 publications · 87 citations

    2

    h-index

  3. 2

    h-index

  4. Drug Metabolism and Pharmacokinetics

    DMPK · 1 publications · 13 citations

    1

    h-index

  5. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 1 publications · 33 citations

    1

    h-index

1–5