Concepedia

Nkg2d-mediated Recognition

NKG2D-Mediated Recognition is a molecular immune recognition mechanism in which the activating receptor NKG2D on natural killer cells and cytotoxic T cells selectively binds to stress-induced ligands expressed on compromised or transformed cells, thereby initiating targeted immune surveillance against malignancies.

982

Publications

86.2K

Citations

5.7K

Authors

1.3K

Institutions

Publications per year

2017–2026

241

Parents

Publications

982

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

Veronika Groh, Jennifer D. Wu, Cassian Yee et al. · Nature · 2002 · 1.6K citations

, , +15

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

Stephan Gasser, Sandra Oršulić, Eric J. Brown et al. · Nature · 2005 · 1.3K citations · Full text

, , +16

ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor

David Cosman, Jürgen Müllberg, Claire L. Sutherland et al. · Immunity · 2001 · 1.2K citations · Full text

, , +16

Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

Andreas Diefenbach, Eric R. Jensen, A. M. Jamieson et al. · Nature · 2001 · 1.1K citations · Full text

, , +14

Regulation of Cutaneous Malignancy by γδ T Cells

Michael Girardi, David Oppenheim, Carrie R. Steele et al. · Science · 2001 · 973 citations · Full text

, , +16

1–5 of 982

Authors

5.7K

  1. AS
    Alexander Steinle

    University of Tübingen, Germany

    39 publications · 7.2K citations

    33

    h-index

  2. DH
    David H. Raulet

    University of California, Berkeley, United States

    30 publications · 6.7K citations

    25

    h-index

  3. LL
    Lewis L. Lanier

    University of California, San Francisco, United States

    30 publications · 4K citations

    24

    h-index

  4. TA
    Thomas A. Spies

    Pacific Northwest Research Station, United States

    24 publications · 6.1K citations

    22

    h-index

  5. VG
    Veronika Groh

    Fred Hutch Cancer Center, United States

    24 publications · 5.5K citations

    20

    h-index

1–5 of 5.7K

Institutions

1.3K

  1. Inserm

    Paris, France

    33 h-index

    324 publications

    37.4K citations

  2. University of Tübingen

    Tübingen, Germany

    30 h-index

    134 publications

    26.4K citations

  3. Fred Hutch Cancer Center

    Seattle, United States

    27 h-index

    103 publications

    25.5K citations

  4. University of California, Berkeley

    Berkeley, United States

    26 h-index

    133 publications

    27.5K citations

  5. University of California, San Francisco

    San Francisco, United States

    25 h-index

    111 publications

    12.8K citations

  6. Harvard University

    Cambridge, United States

    22 h-index

    94 publications

    16.6K citations

  7. University of Genoa

    Genoa, Italy

    22 h-index

    110 publications

    20.9K citations

  8. Istituto Giannina Gaslini

    Genoa, Italy

    22 h-index

    75 publications

    19K citations

1–8 of 1.3K

Venues

  1. The Journal of Immunology

    JI · 117 publications · 13.1K citations

    67

    h-index

  2. European Journal of Immunology

    EJI · 46 publications · 3K citations

    29

    h-index

  3. PLoS ONE

    37 publications · 2.1K citations

    28

    h-index

  4. Blood

    33 publications · 5.5K citations

    27

    h-index

  5. Frontiers in Immunology

    48 publications · 2.1K citations

    27

    h-index

1–5