Concepedia

Niche Plasticity

Niche Plasticity is the dynamic adaptability of the cancer stem cell niche, defined as its capacity to undergo structural and functional alterations in response to microenvironmental cues, thereby modulating stemness, tumorigenicity, and therapeutic resistance within the tumor ecosystem.

106

Publications

8.4K

Citations

579

Authors

286

Institutions

Publications per year

2017–2026

41

Parents

Publications

106

Dominant role of the niche in melanocyte stem-cell fate determination

Emi K. Nishimura, Siobhán A. Jordan, Hideo Oshima et al. · Nature · 2002 · 880 citations

, , +14

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

Takashi Seino, Shintaro Kawasaki, Mariko Shimokawa et al. · Cell stem cell · 2018 · 638 citations

, , +14

Niche stiffness underlies the ageing of central nervous system progenitor cells

Michael Segel, Björn Neumann, Myfanwy F. E. Hill et al. · Nature · 2019 · 540 citations · Full text

, , +14

The Role of the Extracellular Matrix in Cancer Stemness

Sameera Nallanthighal, James Patrick Heiserman, Dong‐Joo Cheon · Frontiers in Cell and Developmental Biology · 2019 · 334 citations · Full text

, , +17

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

Arianna Fumagalli, Koen C. Oost, Lennart Kester et al. · Cell stem cell · 2020 · 309 citations · Full text

, , +17

1–5 of 106

Authors

579

  1. RA
    Robert A. Gatenby

    Moffitt Cancer Center, United States

    2 publications · 49 citations

    2

    h-index

  2. DA
    David Aurioles‐Gamboa

    Instituto Politécnico Nacional, Mexico

    2 publications · 106 citations

    2

    h-index

  3. PH
    Peter Haase

    Senckenberg Research Institute and Natural History Museum Frankfurt/M, Germany

    2 publications · 76 citations

    2

    h-index

  4. AR
    Alexander R.A. Anderson

    Moffitt Cancer Center, United States

    2 publications · 38 citations

    2

    h-index

  5. ME
    Mark E. Warner

    University of Delaware, United States

    2 publications · 109 citations

    2

    h-index

1–5 of 579

Institutions

286

  1. Heidelberg University

    Heidelberg, Germany

    4 h-index

    19 publications

    2.6K citations

  2. University of Exeter

    Exeter, United Kingdom

    3 h-index

    3 publications

    193 citations

  3. Senckenberg Research Institute and Natural History Museum Frankfurt/M

    Frankfurt am Main, Germany

    3 h-index

    7 publications

    230 citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    3 h-index

    8 publications

    145 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    12 publications

    209 citations

  6. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    3 publications

    211 citations

  7. Moffitt Cancer Center

    Tampa, United States

    3 h-index

    5 publications

    114 citations

  8. Rutgers, The State University of New Jersey

    New Brunswick, United States

    2 h-index

    12 publications

    244 citations

1–8 of 286

Venues

  1. Nature

    3 publications · 1.5K citations

    3

    h-index

  2. Journal of Theoretical Biology

    3 publications · 92 citations

    3

    h-index

  3. Hydrobiologia

    3 publications · 104 citations

    3

    h-index

  4. Ecological Modelling

    2 publications · 97 citations

    2

    h-index

  5. The ISME Journal

    2 publications · 452 citations

    2

    h-index

1–5