Koen C. Oost

High-resolution 3D imaging of fixed and cleared organoids

Johanna F. Dekkers, María Alieva, Lianne M. Wellens et al. · Nature Protocols · 2019 · 535 citations

Tissue Imaging, Radiology, Engineering +11

Interplay between metabolic identities in the intestinal crypt supports stem cell function

Maria J. Rodríguez Colman, Matthias Schewe, Maaike Meerlo et al. · Nature · 2017 · 499 citations

Developmental Biology, Medicine, Adult Stem Cell +10

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

Arianna Fumagalli, Koen C. Oost, Lennart Kester et al. · Cell stem cell · 2020 · 299 citations · Full text

Integrative multi‐omics analysis of intestinal organoid differentiation

Rik G.H. Lindeboom, Lisa van Voorthuijsen, Koen C. Oost et al. · Molecular Systems Biology · 2018 · 151 citations · Full text

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression

Arianna Fumagalli, Saskia J.E. Suijkerbuijk, Harry Begthel et al. · Nature Protocols · 2018 · 100 citations

Surgical Oncology, Intestinal Transplantation, Xenotransplantation +10