Concepedia

Next-generation Sequencing-based Detection

Next-Generation Sequencing-Based Detection is a methodological framework within molecular diagnostics that leverages high-throughput sequencing technologies to identify cancer-associated genetic alterations at the DNA or RNA level with enhanced sensitivity and scalability compared to traditional sequencing approaches.

1.3K

Publications

72.3K

Citations

12.3K

Authors

2.6K

Institutions

Publications per year

2017–2026

837

Parents

Publications

1.3K

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

Jeanne Tie, Yuxuan Wang, Cristian Tomasetti et al. · Science Translational Medicine · 2016 · 1.5K citations · Full text

, , +17

VarScan: variant detection in massively parallel sequencing of individual and pooled samples

Daniel C. Koboldt, Ken Chen, Todd Wylie et al. · Bioinformatics · 2009 · 1.4K citations · Full text

, , +17

Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling

Aadel A. Chaudhuri, Jacob J. Chabon, Alexander F. Lovejoy et al. · Cancer Discovery · 2017 · 1.1K citations · Full text

, , +17

Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy

Frédéric FIORE, Frédéric Blanchard, F. Charbonnier et al. · British Journal of Cancer · 2007 · 734 citations · Full text

, , +17

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

Deniz Pekin, Yousr Skhiri, Jean‐Christophe Baret et al. · Lab on a Chip · 2011 · 525 citations

, , +17

1–5 of 1.3K

Authors

12.3K

  1. KP
    Keyur P. Patel

    The University of Texas MD Anderson Cancer Center, United States

    11 publications · 1.1K citations

    11

    h-index

  2. RL
    Rajyalakshmi Luthra

    The University of Texas MD Anderson Cancer Center, United States

    11 publications · 1.2K citations

    11

    h-index

  3. MJ
    Mark J. Routbort

    The University of Texas MD Anderson Cancer Center, United States

    10 publications · 1K citations

    10

    h-index

  4. TY
    Takayuki Yoshino

    National Cancer Center Hospital East, Japan

    9 publications · 757 citations

    9

    h-index

  5. GR
    Geoffrey R. Oxnard

    Dana-Farber Cancer Institute, United States

    8 publications · 905 citations

    8

    h-index

1–5 of 12.3K

Institutions

2.6K

  1. Inserm

    Paris, France

    30 h-index

    253 publications

    28.3K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    29 h-index

    310 publications

    34K citations

  3. Massachusetts General Hospital

    Boston, United States

    29 h-index

    189 publications

    14.3K citations

  4. Harvard University

    Cambridge, United States

    28 h-index

    204 publications

    20.7K citations

  5. Stanford University

    Stanford, United States

    27 h-index

    151 publications

    42.7K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    25 h-index

    167 publications

    19.8K citations

  7. Johns Hopkins University

    Baltimore, United States

    24 h-index

    223 publications

    16.3K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    21 h-index

    120 publications

    12.2K citations

1–8 of 2.6K

Venues

  1. Journal of Molecular Diagnostics

    JMD · 59 publications · 3.3K citations

    33

    h-index

  2. PLoS ONE

    54 publications · 3.2K citations

    31

    h-index

  3. Scientific Reports

    34 publications · 1.5K citations

    24

    h-index

  4. Clinical Cancer Research

    24 publications · 2.6K citations

    22

    h-index

  5. Oncotarget

    31 publications · 1.4K citations

    22

    h-index

1–5