Concepedia

Negative Selection Regimes

Negative Selection Regimes is a theoretical framework in evolutionary biology that specifies the conditions under which natural selection acts to eliminate deleterious alleles from a population, distinguishing it from other selection regimes by its focus on the removal rather than promotion of genetic variants.

75

Publications

7.6K

Citations

285

Authors

149

Institutions

Publications per year

2017–2026

17

Variants

Purifying Selection Regimes

Parents

Publications

75

A new approach to variable selection in least squares problems

M. R. Osborne · IMA Journal of Numerical Analysis · 2000 · 862 citations

, , +15

Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

Steven Gazal, Hilary K. Finucane, Nicholas A. Furlotte et al. · Nature Genetics · 2017 · 617 citations · Full text

, , +16

Who Benefits Most from College?

Jennie E. Brand, Yu Xie · American Sociological Review · 2010 · 590 citations · Full text

, , +13

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system.

Craig A. Mullen, Mogens Kilstrup, R. Michael Blaese · Proceedings of the National Academy of Sciences · 1992 · 505 citations

, , +14

Signatures of negative selection in the genetic architecture of human complex traits

Jian Zeng, Ronald de Vlaming, Yang Wu et al. · Nature Genetics · 2018 · 474 citations · Full text

, , +16

1–5 of 75

Authors

285

  1. TM
    Thomas Madsen

    The University of Sydney, Australia

    2 publications · 303 citations

    2

    h-index

  2. CH
    Chia‐Hsun Hsieh

    Chang Gung University, Taiwan

    2 publications · 87 citations

    2

    h-index

  3. QC
    Qingjian Chen

    Sun Yat-sen University, China

    2 publications · 65 citations

    2

    h-index

  4. MW
    Min‐Hsien Wu

    Chang Gung University, Taiwan

    2 publications · 87 citations

    2

    h-index

  5. GA
    Georgii A. Bazykin

    Institute for Information Transmission Problems, Russia

    2 publications · 28 citations

    2

    h-index

1–5 of 285

Institutions

149

  1. Harvard University

    Cambridge, United States

    6 h-index

    27 publications

    7.4K citations

  2. University of Michigan

    Ann Arbor, United States

    4 h-index

    4 publications

    642 citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    7 publications

    727 citations

  4. Institute for Information Transmission Problems

    Moscow, Russia

    2 h-index

    5 publications

    76 citations

  5. University of California, Los Angeles

    Los Angeles, United States

    2 h-index

    5 publications

    702 citations

  6. Massachusetts General Hospital

    Boston, United States

    2 h-index

    8 publications

    708 citations

  7. Chang Gung University

    Taoyuan City, Taiwan

    2 h-index

    18 publications

    761 citations

  8. Universitat Autònoma de Barcelona

    Cerdanyola del Vallès, Spain

    2 h-index

    7 publications

    245 citations

1–8 of 149

Venues

  1. Genome Biology and Evolution

    GBE · 3 publications · 49 citations

    3

    h-index

  2. PLoS ONE

    3 publications · 202 citations

    3

    h-index

  3. Nature Genetics

    3 publications · 1.2K citations

    3

    h-index

  4. Science

    2 publications · 114 citations

    2

    h-index

  5. Genetics

    2 publications · 240 citations

    2

    h-index

1–5