Concepedia

Negative Elongation Factor

Negative Elongation Factor is a regulatory protein complex that induces transcriptional pausing by inhibiting the RNA polymerase II elongation machinery during early transcription.

105

Publications

8.1K

Citations

559

Authors

199

Institutions

Publications per year

2017–2026

29

Variants

Nelf

Parents

Publications

105

Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation

Bryan A. Gibson, Yajie Zhang, Hong Jiang et al. · Science · 2016 · 373 citations · Full text

, , +17

Dynamics of Human Immunodeficiency Virus Transcription: P-TEFb Phosphorylates RD and Dissociates Negative Effectors from the Transactivation Response Element

Koh Fujinaga, Dan Irwin, Ye-Hong Huang et al. · Molecular and Cellular Biology · 2003 · 363 citations · Full text

, , +15

NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly

Daniel A. Gilchrist, Sergei Nechaev, Chanhyo Lee et al. · Genes & Development · 2008 · 310 citations · Full text

, , +17

Defining the Status of RNA Polymerase at Promoters

Leighton J. Core, Joshua J. Waterfall, Daniel A. Gilchrist et al. · Cell Reports · 2012 · 269 citations · Full text

, , +17

RNA Polymerase II Elongation Control

Jiexin Peng, Mingyi Liu, Jon E. Marion et al. · Cold Spring Harbor Symposia on Quantitative Biology · 1998 · 239 citations

, , +17

1–5 of 105

Authors

559

  1. YY
    Yuki Yamaguchi

    Tokyo Institute of Technology, Japan

    13 publications · 1.4K citations

    13

    h-index

  2. HH
    Hiroshi Handa

    Tokyo Institute of Technology, Japan

    12 publications · 1.5K citations

    12

    h-index

  3. TW
    Tadashi Wada

    Tokyo Institute of Technology, Japan

    8 publications · 1.1K citations

    8

    h-index

  4. DS
    David S. Gilmour

    Pennsylvania State University, United States

    7 publications · 770 citations

    7

    h-index

  5. RL
    Rong Li

    The University of Texas at San Antonio Health Science Center, United States

    6 publications · 241 citations

    6

    h-index

1–5 of 559

Institutions

199

  1. Tokyo Institute of Technology

    Tokyo, Japan

    15 h-index

    57 publications

    6.6K citations

  2. Cornell University

    Ithaca, United States

    11 h-index

    44 publications

    4.6K citations

  3. Pennsylvania State University

    State College, United States

    8 h-index

    21 publications

    2.1K citations

  4. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    8 h-index

    34 publications

    1.2K citations

  5. National Institutes of Health

    Bethesda, United States

    6 h-index

    22 publications

    2.9K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    14 publications

    2.7K citations

  7. University of Iowa

    Iowa City, United States

    5 h-index

    15 publications

    2K citations

  8. University of California, Berkeley

    Berkeley, United States

    5 h-index

    19 publications

    2.2K citations

1–8 of 199

Venues

  1. Molecular and Cellular Biology

    MCB · 11 publications · 1.5K citations

    11

    h-index

  2. Journal of Biological Chemistry

    JBC · 11 publications · 801 citations

    11

    h-index

  3. Nature Communications

    9 publications · 547 citations

    9

    h-index

  4. Molecular Cell

    6 publications · 498 citations

    6

    h-index

  5. Nucleic Acids Research

    6 publications · 387 citations

    6

    h-index

1–5