Concepedia

Negative Clock Regulators

Negative Clock Regulators is a class of regulatory proteins that function within the circadian clock mechanism by inhibiting the transcriptional activity of core clock genes, thereby providing feedback necessary for the generation and maintenance of circadian rhythms.

68

Publications

7.7K

Citations

356

Authors

135

Institutions

Publications per year

2017–2026

19

Parents

Publications

68

mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop

Kazuhiko Kume, Mark J. Zylka, Sriram Sathyanarayanan et al. · Cell · 1999 · 1.6K citations · Full text

, , +16

Nuclear Receptor Rev-erbα Is a Critical Lithium-Sensitive Component of the Circadian Clock

Lei Yin, Jing Wang, Peter S. Klein et al. · Science · 2006 · 549 citations

, , +17

A Molecular Mechanism for Circadian Clock Negative Feedback

Hao A. Duong, María S. Robles, Darko Knutti et al. · Science · 2011 · 361 citations

, , +13

KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria

Hideo Iwasaki, Taeko Nishiwaki, Yohko Kitayama et al. · Proceedings of the National Academy of Sciences · 2002 · 318 citations · Full text

, , +16

Control of Intracellular Dynamics of Mammalian Period Proteins by Casein Kinase I ε (CKIε) and CKIδ in Cultured Cells

Makoto Akashi, Yoshiki Tsuchiya, Takao Yoshino et al. · Molecular and Cellular Biology · 2002 · 293 citations · Full text

, , +16

1–5 of 68

Authors

356

  1. JD
    Jay Dunlap

    Dartmouth College, United States

    5 publications · 378 citations

    5

    h-index

  2. JL
    Jennifer Loros

    Dartmouth College, United States

    4 publications · 277 citations

    4

    h-index

  3. MH
    Michael H. Hastings

    MRC Laboratory of Molecular Biology, United Kingdom

    4 publications · 1.7K citations

    4

    h-index

  4. CL
    Choogon Lee

    Florida State University, United States

    4 publications · 544 citations

    4

    h-index

  5. ES
    Elizabeth S. Maywood

    MRC Laboratory of Molecular Biology, United Kingdom

    3 publications · 1.7K citations

    3

    h-index

1–5 of 356

Institutions

135

  1. Harvard University

    Cambridge, United States

    6 h-index

    26 publications

    14.4K citations

  2. The University of Tokyo

    Tokyo, Japan

    4 h-index

    12 publications

    998 citations

  3. Japan Science and Technology Agency

    Tokyo, Japan

    4 h-index

    22 publications

    4.8K citations

  4. Dartmouth College

    Hanover, United States

    4 h-index

    12 publications

    1K citations

  5. Pontificia Universidad Católica de Chile

    Santiago, Chile

    3 h-index

    10 publications

    503 citations

  6. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    3 h-index

    10 publications

    209 citations

  7. Nagoya University

    Nagoya, Japan

    3 h-index

    14 publications

    2.4K citations

  8. Kyoto University

    Kyoto, Japan

    3 h-index

    5 publications

    985 citations

1–8 of 135

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 800 citations

    5

    h-index

  2. Journal of Biological Chemistry

    JBC · 4 publications · 488 citations

    4

    h-index

  3. PLoS ONE

    4 publications · 231 citations

    4

    h-index

  4. Journal of Biological Rhythms

    JBR · 4 publications · 245 citations

    4

    h-index

  5. Science

    3 publications · 1.1K citations

    3

    h-index

1–5