Concepedia

N-hexane Toxicity

N-Hexane Toxicity is a toxicological phenomenon characterized by the neurotoxic effects resulting from metabolic conversion of n-hexane to 2,5-hexanedione, which induces axonal degeneration through protein adduct formation and subsequent peripheral neuropathy.

202

Publications

6.9K

Citations

800

Authors

276

Institutions

Publications per year

2017–2026

33

Parents

Publications

202

N-Hexane Neuropathy

Allan Herskowitz, Nobuyoshi Ishii, Herbert H. Schaumburg · New England Journal of Medicine · 1971 · 298 citations

, , +16

DEGENERATION IN CENTRAL AND PERIPHERAL NERVOUS SYSTEMS PRODUCED BY PURE <i>n</i>-HEXANE: AN EXPERIMENTAL STUDY

Herbert H. Schaumburg, Peter S. Spencer · Brain · 1976 · 217 citations

, , +13

The relative neurotoxicity of methyl-n-butyl ketone, n-hexane and their metabolites

Walter J. Krasavage, John L. O’Donoghue, G.D. DiVincenzo et al. · Toxicology and Applied Pharmacology · 1980 · 216 citations

, , +14

Glue-Sniffing Neuropathy

Rowena Korobkin, Arthur K. Asbury, A. J. Sumner et al. · Archives of Neurology · 1975 · 199 citations

, , +17

Covalent binding of a neurotoxic n-hexane metabolite: Conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione

Anthony P. DeCaprio, Eugene J. Olajos, Peter Weber · Toxicology and Applied Pharmacology · 1982 · 135 citations

, , +12

1–5 of 202

Authors

800

  1. YT
    Yasuhiro Takeuchi

    Shizuoka University, Japan

    12 publications · 479 citations

    11

    h-index

  2. LP
    Luigi Perbellini

    University of Verona, Italy

    7 publications · 225 citations

    7

    h-index

  3. FB
    F Brugnone

    University of Verona, Italy

    6 publications · 173 citations

    6

    h-index

  4. NH
    Naomi Hisanaga

    Nagoya University, Japan

    5 publications · 186 citations

    5

    h-index

  5. KX
    Keqin Xie

    Shandong University, China

    5 publications · 81 citations

    5

    h-index

1–5 of 800

Institutions

276

  1. Nagoya University

    Nagoya, Japan

    12 h-index

    45 publications

    1.7K citations

  2. University of Verona

    Verona, Italy

    7 h-index

    26 publications

    736 citations

  3. Shandong University

    Jinan, China

    6 h-index

    31 publications

    523 citations

  4. Dalian Medical University

    Dalian, China

    5 h-index

    50 publications

    1.1K citations

  5. University of Padua

    Padua, Italy

    5 h-index

    21 publications

    606 citations

  6. University of Pavia

    Pavia, Italy

    4 h-index

    10 publications

    403 citations

  7. University of Alicante

    Alicante, Spain

    3 h-index

    8 publications

    204 citations

  8. Universidade de São Paulo

    São Paulo, Brazil

    3 h-index

    4 publications

    78 citations

1–8 of 276

Venues

  1. 14

    h-index

  2. PubMed

    Repository · 14 publications · 318 citations

    13

    h-index

  3. Toxicology and Applied Pharmacology

    TAAP · 8 publications · 559 citations

    8

    h-index

  4. Occupational and Environmental Medicine

    8 publications · 390 citations

    8

    h-index

  5. PLoS ONE

    5 publications · 160 citations

    5

    h-index

1–5