Concepedia

Mutational Analysis Of Complex Stability

Mutational Analysis of Complex Stability is a methodological framework within structural and molecular biology that systematically evaluates the effects of amino acid substitutions on the thermodynamic and functional integrity of protein complexes to determine residue-level contributions to complex formation and stability.

36

Publications

1.2K

Citations

157

Authors

63

Institutions

Publications per year

2017–2026

3

Parents

Publications

36

Dissecting the Energetics of the Apoflavodoxin-FMN Complex

Anabel Lostao, Mohamed El Harrous, Fatna Daoudi et al. · Journal of Biological Chemistry · 2000 · 78 citations · Full text

, , +13

Analysis of Binding Interactions in an Idiotope−Antiidiotope Protein−Protein Complex by Double Mutant Cycles

Ellen R. Goldman, William F. Dall’Acqua, Bradford C. Braden et al. · Biochemistry · 1997 · 67 citations

, , +16

Probing the mechanistic role of the long α‐helix in subunit L of respiratory Complex I from <i>Escherichia coli</i> by site‐directed mutagenesis

Galina Belevich, Michael I. Verkhovsky, Mårten Wikström et al. · Molecular Microbiology · 2011 · 64 citations · Full text

, , +13

Thermodynamic and Fluorescence Analyses to Determine Mechanisms of IgG1 Stabilization and Destabilization by Arginine

Masakazu Fukuda, Daisuke Kameoka, Takuya Torizawa et al. · Pharmaceutical Research · 2013 · 63 citations

, , +16

Mutational Analyses Define Helix Organization and Key Residues of a Bacterial Membrane Energy-transducing Complex

Emilie L. Goemaere, Eric Cascalès, Roland Lloubès · Journal of Molecular Biology · 2006 · 62 citations

, , +11

1–5 of 36

Authors

157

  1. VL
    Victor L. Davidson

    University of Mississippi Medical Center, United States

    2 publications · 37 citations

    2

    h-index

  2. WF
    William F. Dall’Acqua

    AstraZeneca (Germany), Germany

    2 publications · 127 citations

    2

    h-index

  3. LH
    Limei H. Jones

    University of Mississippi Medical Center, United States

    2 publications · 37 citations

    2

    h-index

  4. ME
    M. Elizabeth Graichen

    University of Mississippi Medical Center, United States

    2 publications · 37 citations

    2

    h-index

  5. HZ
    Hai‐Meng Zhou

    Tsinghua University, China

    1 publications · 28 citations

    1

    h-index

1–5 of 157

Institutions

63

  1. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    9 publications

    276 citations

  2. University of Mississippi Medical Center

    Jackson, United States

    2 h-index

    9 publications

    175 citations

  3. Institut de Biologie Structurale

    Grenoble, France

    2 h-index

    9 publications

    276 citations

  4. University of Pavia

    Pavia, Italy

    2 h-index

    6 publications

    184 citations

  5. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    4 publications

    110 citations

  6. Tokyo Medical and Dental University

    Tokyo, Japan

    2 h-index

    7 publications

    141 citations

  7. National Institute of Technology Warangal

    Warangal, India

    1 h-index

    2 publications

    32 citations

  8. Helsinki Institute of Physics

    Helsinki, Finland

    1 h-index

    5 publications

    320 citations

1–8 of 63

Venues

  1. Biochemistry

    10 publications · 341 citations

    10

    h-index

  2. Journal of Biological Chemistry

    JBC · 5 publications · 214 citations

    5

    h-index

  3. FEBS Letters

    5 publications · 135 citations

    5

    h-index

  4. Journal of Chemical Information and Modeling

    JCIM · 2 publications · 81 citations

    2

    h-index

  5. Protein Science

    PS · 2 publications · 39 citations

    2

    h-index

1–5