William F. Dall’Acqua

Properties of Human IgG1s Engineered for Enhanced Binding to the Neonatal Fc Receptor (FcRn)

William F. Dall’Acqua, Peter A. Kiener, Herren Wu · Journal of Biological Chemistry · 2006 · 637 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Bound water molecules and conformational stabilization help mediate an antigen-antibody association.

Thirumaleshwara N. Bhat, G.A. Bentley, G. Boulot et al. · Proceedings of the National Academy of Sciences · 1994 · 480 citations

Life Sciences, Biochemistry, Biophysics +17

A Novel Investigational Fc-Modified Humanized Monoclonal Antibody, Motavizumab-YTE, Has an Extended Half-Life in Healthy Adults

Gabriel J. Robbie, Ryan Criste, William F. Dall’Acqua et al. · Antimicrobial Agents and Chemotherapy · 2013 · 353 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms

Vaheh Oganesyan, Melissa Damschroder, Kimberly E. Cook et al. · Journal of Biological Chemistry · 2014 · 254 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Structural characterization of a human Fc fragment engineered for lack of effector functions

Vaheh Oganesyan, Changshou Gao, Lena Shirinian et al. · Acta Crystallographica Section D Biological Crystallography · 2008 · 197 citations · Full text

Pharmacy, Immunology, Molecular Biology +15