Concepedia

Mutation Accumulation Dynamics

Mutation Accumulation Dynamics is a theoretical framework within evolutionary trajectory analysis that characterizes the progressive and probabilistic acquisition of genetic alterations over time in a population, distinguishing itself by modeling the temporal patterns and selective constraints governing the fixation or persistence of neutral or nearly neutral mutations.

259

Publications

18.8K

Citations

930

Authors

444

Institutions

Publications per year

2017–2026

73

Parents

Publications

259

Beneficial Mutation–Selection Balance and the Effect of Linkage on Positive Selection

Michael M. Desai, Daniel S. Fisher · Genetics · 2007 · 649 citations · Full text

, , +17

Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer

Gillian Smith, Francis A. Carey, Julie Beattie et al. · Proceedings of the National Academy of Sciences · 2002 · 522 citations

, , +17

The evolutionary dynamics and fitness landscape of clonal hematopoiesis

Caroline J. Watson, Alana Papula, Gladys Y. P. Poon et al. · Science · 2020 · 460 citations

, , +17

MUTATIONAL MELTDOWNS IN SEXUAL POPULATIONS

Michael Lynch, John S. Conery, Reinhard Bürger · Evolution · 1995 · 446 citations

, , +13

Parasitism, mutation accumulation and the maintenance of sex

R. Stephen Howard, Curtis M. Lively · Nature · 1994 · 382 citations

, , +12

1–5 of 259

Authors

930

  1. ML
    Michael Lynch

    Indiana University Bloomington, United States

    16 publications · 2.2K citations

    16

    h-index

  2. CF
    Charles F. Baer

    University of Florida, United States

    7 publications · 294 citations

    7

    h-index

  3. IG
    Isabel Gordo

    Instituto Gulbenkian de Ciência, Portugal

    7 publications · 678 citations

    7

    h-index

  4. MM
    Michael M. Desai

    Harvard University, United States

    6 publications · 1.2K citations

    6

    h-index

  5. SS
    Sarah Schaack

    Reed College, United States

    5 publications · 148 citations

    5

    h-index

1–5 of 930

Institutions

444

  1. Indiana University Bloomington

    Bloomington, United States

    13 h-index

    33 publications

    3.4K citations

  2. Harvard University

    Cambridge, United States

    11 h-index

    22 publications

    3.5K citations

  3. University of Oregon

    Eugene, United States

    11 h-index

    22 publications

    3K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    29 publications

    1K citations

  5. University of California, Irvine

    Irvine, United States

    10 h-index

    35 publications

    2K citations

  6. University of Edinburgh

    Edinburgh, United Kingdom

    10 h-index

    26 publications

    2.1K citations

  7. University of Florida

    Gainesville, United States

    8 h-index

    51 publications

    2.6K citations

  8. Instituto Gulbenkian de Ciência

    Oeiras, Portugal

    7 h-index

    22 publications

    1.9K citations

1–8 of 444

Venues

  1. Evolution

    29 publications · 2.4K citations

    22

    h-index

  2. Genetics

    22 publications · 2.3K citations

    20

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 17 publications · 2.6K citations

    17

    h-index

  4. Molecular Biology and Evolution

    MBE · 18 publications · 1.1K citations

    17

    h-index

  5. Genetics Research

    7 publications · 716 citations

    7

    h-index

1–5