Concepedia

Multivalent Targeting

Multivalent Targeting is a targeting strategy that involves the simultaneous engagement of multiple ligands or binding agents on a single carrier to enhance specificity and affinity toward target cells or receptors through cooperative molecular interactions.

88

Publications

6.6K

Citations

589

Authors

200

Institutions

Publications per year

2017–2026

31

Parents

Publications

88

Cell-specific targeting of nanoparticles by multivalent attachment of small molecules

Ralph Weissleder, Kimberly M. Kelly, Eric Sun et al. · Nature Biotechnology · 2005 · 902 citations

, , +16

Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis

Matthias Nahrendorf, Farouc A. Jaffer, David E. Sosnovik et al. · Circulation · 2006 · 594 citations · Full text

, , +17

Selective Tumor Cell Targeting Using Low-Affinity, Multivalent Interactions

Coby B. Carlson, Patricia Mowery, Robert M. Owen et al. · ACS Chemical Biology · 2007 · 275 citations

, , +17

Dendritic polyglycerol sulfates as multivalent inhibitors of inflammation

Jens Dernedde, Alexandra Rausch, Marie Weinhart et al. · Proceedings of the National Academy of Sciences · 2010 · 271 citations · Full text

, , +17

Multivalent Endosome Targeting by Homodimeric EEA1

John J. Dumas, Eric Merithew, E. Sudharshan et al. · Molecular Cell · 2001 · 253 citations · Full text

, , +14

1–5 of 88

Authors

589

  1. EW
    E. W. Meijer

    Eindhoven University of Technology, Netherlands

    3 publications · 220 citations

    3

    h-index

  2. DF
    Daan Frenkel

    Institute for Atomic and Molecular Physics, Netherlands

    3 publications · 236 citations

    3

    h-index

  3. TC
    Tine Curk

    University of Cambridge, United Kingdom

    3 publications · 236 citations

    3

    h-index

  4. MM
    Maarten Merkx

    Eindhoven University of Technology, Netherlands

    3 publications · 116 citations

    3

    h-index

  5. SC
    Sun-Ha Cheon

    All India Institute of Medical Sciences, India

    2 publications · 51 citations

    2

    h-index

1–5 of 589

Institutions

200

  1. Eindhoven University of Technology

    Eindhoven, The Netherlands

    5 h-index

    20 publications

    1.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    21 publications

    1.6K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    12 publications

    797 citations

  4. The University of Texas Southwestern Medical Center

    Dallas, United States

    3 h-index

    13 publications

    505 citations

  5. Université Joseph Fourier

    Grenoble, France

    3 h-index

    12 publications

    1.7K citations

  6. Institute of Physics

    Beijing, China

    3 h-index

    6 publications

    313 citations

  7. University of Maryland, Baltimore

    Baltimore, United States

    3 h-index

    10 publications

    344 citations

  8. Harvard University

    Cambridge, United States

    3 h-index

    14 publications

    8.9K citations

1–8 of 200

Venues

  1. Bioconjugate Chemistry

    6 publications · 298 citations

    6

    h-index

  2. Journal of the American Chemical Society

    JACS · 6 publications · 524 citations

    6

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 549 citations

    5

    h-index

  4. Angewandte Chemie International Edition

    4 publications · 135 citations

    5

    h-index

  5. Journal of Biological Chemistry

    JBC · 4 publications · 224 citations

    4

    h-index

1–5