Concepedia

Multiplex Base Editing

Multiplex Base Editing is a genome engineering technique that enables the simultaneous execution of multiple distinct base conversions at spatially separated target sites within a single cellular context, thereby distinguishing it from sequential or single-site base editing approaches.

34

Publications

1.8K

Citations

305

Authors

109

Institutions

Publications per year

2017–2026

34

Parents

Publications

34

Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors

Beau R. Webber, Cara-lin Lonetree, Mitchell G. Kluesner et al. · Nature Communications · 2019 · 227 citations · Full text

, , +17

High-efficiency and multiplex adenine base editing in plants using new TadA variants

Daqi Yan, Bin Ren, Lang Liu et al. · Molecular Plant · 2021 · 143 citations

, , +9

Improved plant cytosine base editors with high editing activity, purity, and specificity

Qiurong Ren, Simon Sretenovic, Guanqing Liu et al. · Plant Biotechnology Journal · 2021 · 142 citations · Full text

, , +17

Modular (de)construction of complex bacterial phenotypes by CRISPR/nCas9-assisted, multiplex cytidine base-editing

Daniel C. Volke, Román A. Martino, Ekaterina Kozaeva et al. · Nature Communications · 2022 · 100 citations · Full text

, , +17

Multiplex base- and prime-editing with drive-and-process CRISPR arrays

Qichen Yuan, Xue Gao · Nature Communications · 2022 · 82 citations · Full text

, , +17

1–5 of 34

Authors

305

  1. XG
    Xue Gao

    Rice University, United States

    3 publications · 158 citations

    3

    h-index

  2. QY
    Qichen Yuan

    Rice University, United States

    3 publications · 158 citations

    3

    h-index

  3. BS
    Branden S. Moriarity

    University of Minnesota, United States

    2 publications · 262 citations

    2

    h-index

  4. GM
    Garrett M. Draper

    University of Minnesota, United States

    2 publications · 262 citations

    2

    h-index

  5. BR
    Beau R. Webber

    University of Minnesota, United States

    2 publications · 262 citations

    2

    h-index

1–5 of 305

Institutions

109

  1. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    36 publications

    1.7K citations

  2. Rice University

    Houston, United States

    3 h-index

    23 publications

    997 citations

  3. Zhejiang University

    Hangzhou, China

    3 h-index

    14 publications

    806 citations

  4. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    14 publications

    905 citations

  5. University of Minnesota

    Minneapolis, United States

    2 h-index

    29 publications

    3.9K citations

  6. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    7 publications

    396 citations

  7. Huazhong Agricultural University

    Wuhan, China

    2 h-index

    5 publications

    58 citations

  8. East China Normal University

    Shanghai, China

    2 h-index

    2 publications

    86 citations

1–8 of 109

Venues

  1. Nature Communications

    8 publications · 579 citations

    8

    h-index

  2. ACS Synthetic Biology

    3 publications · 110 citations

    3

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 54 citations

    2

    h-index

  4. Blood

    1 publications · 65 citations

    1

    h-index

  5. Journal of the American Chemical Society

    JACS · 1 publications · 45 citations

    1

    h-index

1–5