Multi-scale Biological Modeling

Multi-Scale Biological Modeling is a computational and mathematical framework that integrates biological processes across multiple spatial and temporal scales—from molecular and cellular levels to tissue, organ, and organism levels—within a unified model to elucidate complex physiological and pathological mechanisms in systems pharmacology.

716

Publications

37.9K

Citations

2.8K

Authors

1.1K

Institutions

Publications per year

2017–2026

255

Parents

Systems Pharmacology

Children

Coupled Multiphysics ModelingNetwork-based ModelingOrgan ModelingVirtual Physiological HumanWhole-body Pharmacokinetic Modeling

Publications

716

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

Marco Y. Hein, Nina C. Hubner, Ina Poser et al. · Cell · 2015 · 1.4K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology

Michael Feig, John Karanicolas, Charles L. Brooks · Journal of Molecular Graphics and Modelling · 2004 · 887 citations

Life Sciences, Bioinformatics, Biology +11

E-CELL: software environment for whole-cell simulation.

Masaru Tomita, Kazuaki Hashimoto, Kazutoshi Takahashi et al. · Bioinformatics · 1999 · 765 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Nonlinear modelling of cancer: bridging the gap between cells and tumours

John Lowengrub, Hermann B. Frieboes, Fang Jin et al. · Nonlinearity · 2009 · 579 citations · Full text

Medicine, Cancer Biology, Oncology +17

Multi-Scale Modeling of Tissues Using CompuCell3D

Maciej Swat, Gilberto L. Thomas, Julio M. Belmonte et al. · Methods in cell biology · 2012 · 562 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +14

1–5 of 716

Authors

2.8K

PK
Philip K. Maini
University of Oxford, United Kingdom
17 publications · 1.3K citations
16
h-index
PH
Peter Hunter
University of Auckland, New Zealand
16 publications · 773 citations
14
h-index
HM
Helen M. Byrne
University of Oxford, United Kingdom
13 publications · 1.1K citations
13
h-index
TS
Thomas S. Deisboeck
Massachusetts General Hospital, United States
10 publications · 566 citations
10
h-index
JJ
Jennifer J. Linderman
University of Michigan, United States
10 publications · 672 citations
10
h-index

1–5 of 2.8K

Institutions

1.1K

1–8 of 1.1K

Venues

PLoS Computational Biology
37 publications · 1.7K citations
26
h-index
PLoS ONE
35 publications · 1.6K citations
23
h-index
Bioinformatics
22 publications · 2.4K citations
19
h-index
BMC Systems Biology
15 publications · 1.2K citations
15
h-index
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
15 publications · 837 citations
15
h-index

1–5